Figure 3. The effect of L-THP on the cellular accumulation of OXA in mock, MDCK-hOCTN1, and MDCK-hOCT2 cells. In the accumulation study, the cells were incubated with OXA (40 μM) in the absence or presence of L-THP for 5 min. Data are expressed as the mean ± SEM, n = 5. Compared with the mock cells, ###P< 0.001; compared with the OXA-alone group,*P < 0.01 and**P < 0.01,***P < 0.001.