Figure 2. The effect of L-THP on OXA-induced cytotoxicity in mock, MDCK-hOCTN1, and MDCK-hOCT2 cells. Cell viability of mock (a), MDCK-hOCTN1(b), and MDCK-hOCT2 (c) cells. LDH activities in the medium for mock (d), MDCK-hOCTN1 (e), and MDCK-hOCT2 (f) cells. In the toxicity study, the cells were incubated with or without OXA and/or L-THP for 48 h. Data are expressed as the mean ± SEM, n = 5. Compared with the vehicle group,###P < 0.001; compared with the OXA-alone group, **P < 0.01and***P < 0.001.