Figure 5. The effect of L-THP on cytotoxicity (a) and cellular accumulation (b) of OXA in primary DRG cells. Cells were incubated without or with OXA (40 μM) and/or L-THP for 48 h in the cytotoxicity study and for 5 min in the accumulation study. Data are expressed as the mean ± SEM, n = 6 for the cytotoxicity study and n = 5 for the platinum accumulation study. Compared with the vehicle group,###P < 0.001; compared with the OXA-alone group, *P < 0.05,**P < 0.01, and***P < 0.001.