Figure 1. Location of intra-islet heparin sulfate (HS) in control and streptozotocin (STZ)-induced diabetic mice. HS antibodies react with 10E4 [US Biological Cat# H1890, RRID:AB_10013601] (A) or 3G10 (B) epitope. Representative images of HS immunohistochemical staining, HS and insulin (INS), glucagon (GCG), pancreatic polypeptide (PP), somatostatin (SST) staining in islets from control and STZ mice. Immunofluorescence followed by DAPI staining. Scale bar, 50 μm.