Abbreviations
BBB, blood–brain barrier; CD, circular dichroism; CNS: central nervous system; CoQ0, Coenzyme Q0; DCIP: 2, 6-dichloroindophenol; DHO: dihydroorotate; DHODH, dihydroorotate dehydrogenase; FMN, flavin mononucleotide; ITC, isothermal titration calorimetry; MS, multiple sclerosis;