2. Transcription regulation of FT
Structure, development and homeostasis of all organisms cannot be considered without the mechanism of transcriptional regulation because the initiation step from genome to proteome of biological information flow is transcription (Polouliakh, 2019). FT transcriptional regulation is the most competent route to control the flowering period in plants. The expression level of FT can be modified by various TFs of different families such as; MYB , MADS -box,NF-Y , SPL etc which can bind to the promoter region ofFT (Figure 1). The chromatin loops produced at different sites ofFT cis -elements by various TF complexes have been reported as the key determinants for floral transitions initiation. (Cao et al., 2014; Liu et al., 2014). The interaction of TFs with the introns ofFT as well as the 30-downstream region of the coding sequence has also been reported (Figure 1). Furthermore, for different pathways (e.g. photoperiod and thermo-sensory) the vigorous accumulation of H3K4me3, H3K27me3 and H2A.Z are important to transcribe FT (He, 2012). These studies suggest that both TFs and epigenetic regulators are crucial for the transcriptional regulation of FT . However, transcriptional regulation of FT has been studied but very less is known about FT regulation at the protein level.