As with most research, results only generate more questions. There are many more topics to examine relating to the bivalve microbiome. For example, do core microbiome trends hold true across bivalve species? Do they hold true with other suspension feeders (e.g., Crepidula spp.)? Are observed similarities between oyster and mussel microbiomes a result of their shared feeding mechanism? Are observed differences between oyster and mussel microbiomes a result of their genetic differences? Do other marine filter feeders harbor the same numbers and types of bacteria as bivalves? Do they share a core? With continued reference to the eastern oyster, do Crassostrea virginica from other locations (i.e., Chesapeake Bay and Gulf of Mexico) harbor the same bacteria as those in Long Island Sound? How far do spatial trends extend until they are broken? Does the environment impart more of an influence in some locations than in others? Do the core microbiota contribute to specific host physiological functions? Does a high diversity in the gut microbiome inhibit pathogen colonization in the long term? Investigating such questions would be beneficial, resulting in an enhanced understanding of bivalve host–bacterial interactions.