The demographic, biochemical, physiological and clinical characteristics are outlined in Table 1. Patients are stratified according to the overall trend in NT-proBNP level. The demographic and clinical characteristics of the cohort stratified on the echocardiographic phenotype of HF are in Supplementary Table 1.

6 month survival curves stratified by temporal trends of the NT-proBNP levels

Kaplan Meir survival curves stratified according to their temporal trend in their NT-proBNP level through the study period. The log-rank test was used to compare the survival curves. Separate curves were created for HF,HFpEF and HFrEF.(Figure 3)