Understanding the diversity of cytokinesis
I think it is exciting that the recent efforts in Xenopus and Drosophila have revealed how life finds dramatically different solutions to cell division in epithelial tissues (Fig. 2.7 ) \cite{Higashi2016,Herszterg2013,Guillot2013,Founounou2013}. Personally this fascinates me and I want to know all of the different types of cell division that can occur! Looking at cell division at other stages and in other tissues of Xenopus development could be really exciting. It may not seem apparent as to what the usefulness of a survey like this would be, however, I would argue that it is worth pursuing. The researchers exploring the cytokinesis in Drosophila discovered something very exciting about cell division in a tissue and that is that it can be a multicellular process. In the Drosophila tissues explore it is not just the dividing cell that contributes to cell division but the neighboring cells also actively contribute as well. As the cleavage furrow ingresses the neighbors that are being pulled in accumulate Myosin II perpendicular to the axis of division in order to bring the furrowing interfaces close to one another, then the dividing cells polymerizes branched F-actin to push the neighboring cells membrane out of the furrow and adherens junctions are formed between the newly formed daughter cells (Fig.qq).  By investigating cell division in  other types of tissues we could find something equally or even more fascinating, for examples cell division which isn't driven at all by the dividing cell or cell division in a tissue that doesn't require actomyosin.  In less drastic examples, I think it is important to understand how cells undergo cytokinesis in different environments, for example in a highly proliferative intestinal vs the less proliferative skin epithelium. There are also drastic differences in cell shapes of epithelial cells, columnar, cuboidal, squamous, how are these affecting the mechanics of cytokinesis in epithelial cells? I think a simple survey of cell division in several tissues in xenopus and others, just observing actin and Myosin II copuld reveal interesting types of cytokinesis to further investigate.