Inferring genome-wide variation in mutation and selection from polymorphism and divergence data

Abstract

ABSTRACT

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Introduction

Despite half a century spent scrutinizing levels of naturally occuring polymorphism and, more recently, levels of between species divergence at the molecular level, we know embarrassingly little about which forces explain these patterns ( See a recent review (Leffler ) for an overview of the “old riddle”) although some recent analyses on large comprattive dataset su