Nicotinamide Riboside and its Analogs, Tiazofurin and Benzamide Riboside
Nicotinamide riboside, first reported as the lowest molecular weight “V factor” for Haemophilus influenza (Gingrich and Schlenk, 1944), is shown alongside the IMP dehydrogenase prodrugs, tiazofurin (Cooney et al., 1983), and benzamide riboside (Krohn et al., 1992). NMN and its analogs are produced via phosphorylation of the 5′ hydroxyl groups.