Adhere to the Surviving Sepsis Campaign 2016 and other international guidelines for LMIC (WHO ETAT, etc)
● Formalize a process/workflows for clinicians to adhere to after a patient sepsis screen is positive in order to activate bundles.
● Sepsis 3-hour bundle activation for sepsis leads to the following actions:
○ Obtain IV access and obtain blood cultures (if possible)
○ Give oxygen if SpO2 < 90% on room air or < 94% if patient is in shock. If pulse oximeter is not available, use clinical indicators to initiate oxygen therapy
○ Administer appropriate broad spectrum antibiotics according to clinical suspicion and local antibiograms (when available) and preferably within the hour
○ If patient has hypotension or other signs of hypoperfusion, give initial fluid bolus of 30 ml/kg over 30 minutes in adult
○ Monitor clinical signs of perfusion after bolus: BP, skin exam, CR, urine output, AVPU in addition to vital signs
○ If hypotension resolved, then resume maintenance fluid and monitoring every 1-2 hours.
○ If hypotension persists, then activate 6-hour sepsis bundle