Kirigami-inspired hand exoskeletal system for rehabilitation has not been fully utilized in the field of biomedical engineering. This paper aims to validate that kirigami-inspired hand exoskeletal system can be a potential in rehabilitation process for stroke patients. A prototype was create to validate this problem and experiments were conducted and analysed. The results of the experiment has shown that the origami/kirigami-inspired hand exoskeletal system has the potential to be used in rehabilitation process through limited clenching and also have potentials in utilizing this design in other fields of application.