Of each study finally included the following variables were collected: year of publication, specialty, country, number of patients included, age, gender, type of study, type of publication, follow-up performed, main outcome, drugs, reported efficacy, type of CAPS (FCAS, MWS, CINCA, overlap syndrome FCA-MWS, MWS-CINCA, undifferentiated, not informed), mutation studied, if applicable, language of the publication and inclusion / exclusion criteria.
Protocol vs. overview
Our planned search strategy published in Dermatology and Therapy journal was compared with the final reported review methods. Due to time and funding limitations, we decided to select only studies published in English. Finally, the authors of the studies were not contacted due to time limitations.