All authors wish to emphasize that:
The manuscript does/does not contain experiments using animals. The permission of the national or local authorities (giving the permission or the accreditation no. of the laboratory and of the investigator) should be stated if animal experiments are included. If no such rules or permissions have been implicated in the particular country, this must be stated. www.biotechnology-journal.com Manuscript submission: http://mc.manuscriptcentral.com/btj Contact the Editorial Office at: btj@wiley.com Page 7 of 18 vi) The manuscript does/does not contain human studies. If such studies are included, it should be stated that local Ethical Committee approval was received for the studies and that the informed consent of all participating subjects was obtained. Permission statements relating to points 4 and 5 should also be included in the text of the manuscript.