Glucose Metabolism in Alzheimer’s disease: From Neuron to Brain

Alzheimer’s disease (AD) is an incapacitating condition that impairs cognition and behavior, ultimately resulting in death. It is the 6th leading cause of death in the United States:  it affects more than 5 million Americans, but a disease modifying treatment does not exist. AD is characterized by progressive neurodegeneration associated with amyloid plaque formation and tangle deposition in the cortex and hippocampus of the brain