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\begin{document}

\title{Cell Template}



\author[1]{Emma Molls}%
\affil[1]{University of Minnesota}%


\vspace{-1em}



  
  \date{May 26, 2024}


\begingroup
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\selectlanguage{english}
\begin{abstract}
{This Authorea document template can be used to prepare documents
according to a desired citation style and authoring guidelines.
Abstracts are not always required, but most academic papers have one and
writers should know how to produce a useful abstract. An abstract should
be a very short, clear and concise summation of the entire paper. An
abstract should provide enough of a preview that a typical reader will
know whether or not they wish to read the paper. It should reveal both
the purpose and conclusions of the paper.}\\%
\end{abstract}%



\sloppy


\par\null

\subsection*{General Article Organization and Text
Specifications}\label{general-article-organization-and-text-specifications}

\emph{Cell}~full-length~articles generally contain the following
sections in this order: Title Authors Affiliations Contact Information
Additional Title Page Footnotes Summary Introduction Results Discussion
Author Contributions Acknowledgments~References Figure and Table Legends
STAR Methods Figures and Tables Graphical Abstract and Supplemental
Information. The text (title through legends) should be provided as one
document which may also contain the tables. Figures should be provided
separately.~\href{http://www.cell.com/cell/supplemental-information}{Supplemental
Information}~should be provided separately.The total character count of
the main text should not exceed 55000 characters. This limit includes
all text (and the spaces between words) in the title author list
affiliations Summary Introduction~Results Discussion Author
Contributions Acknowledgments References and main figure legends but
excludes STAR Methods text and supplemental item legends.An article may
contain up to seven figures and/or tables. Gene symbols should be
italicized; protein products of the loci are not italicized. Nonstandard
abbreviations should be defined when first used in the text. Use of
abbreviations should be kept at a minimum. Manuscript file types that we
can accept for submission include Word RTF and TXT. Required items
differ for each article type and are specified during the submission
process.Please note that the text should be double spaced and pages
should be numbered. Although summaries need to be entered as text files
separate from the body of the manuscript during the online submission
process they should also be included within the manuscript file as
usual.\textbf{Manuscripts that do not conform to the format guidelines
may be returned to the authors for reformatting.}

{}

\subsection*{Preparation of Specific
Sections}

\subsubsection*{}

\subsubsection*{Title}

{\label{759598}}

The title should capture the conceptual significance for a broad
audience. As a general guideline the most effective titles are no more
than 10--12 words and should readily give readers an overall view of the
paper's significance rather than the detailed contents of the paper
which can be elaborated upon in the Summary. Titles should also avoid
use of jargon uncommon abbreviations and punctuation. Titles can occupy
no more than three lines of type; each line should contain no more than
50 characters including spaces.

\subsubsection*{}

\subsubsection*{Authors/Affiliations}

{\label{367163}}

Author names should be spelled out rather than set in initials. Authors
should be footnoted to corresponding affiliations. Affiliations should
contain the following core information: department(s)/subunit(s);
institution; city state/region postal code; country.~Note: Please check
author names and affiliations carefully as we cannot amend or correct
these sections after publication.

\subsubsection*{}

\subsubsection*{Corresponding Author}

{\label{785503}}

The ``Correspondence'' line should include the e-mail address of the
corresponding author(s). One corresponding author is preferred for
reasons stated in the Authorship section of Editorial Policies above.
But there is no mandatory limit on the number of corresponding authors
that may be listed.~Corresponding authors may also provide a Twitter
handle as a secondary means of contact. Please see the corresponding
author responsibilities noted above in the Editorial Policies.

\subsubsection*{}

\subsubsection*{Lead Contact}

{\label{390577}}

Every author list must identify one corresponding author as a Lead
Contact noted by a footnote in the manuscript. If there is only one
corresponding author that author will be listed as the Lead Contact.
Please see the Lead Contact responsibilities noted above in the
Authorship section of the Editorial Policies.

\subsubsection*{}

\subsubsection*{Additional Footnotes}

{\label{540241}}

Footnotes are only allowed on page 1 of the text (and in tables). They
may include a Lead Contact (mandatory) or a present address (optional)
or they may indicate co-first authorship (optional).~For more on
designations of author contributions please see the ``Authorship''
section above under Editorial Policies.

\subsubsection*{}

\subsubsection*{Summary}

{\label{603590}}

The Summary consists of a single paragraph of fewer than 150 words. We
recommend that effective abstracts include the following elements: (1) a
brief background of the question while avoiding common yet
information-poor clauses stating that a certain process has not been
well understood; (2) a description of the results and approaches/model
systems framed in the context of their conceptual interest; and (3) an
indication of the broader significance of the work. As the adjective
``novel'' tends to be overused and rarely adds much meaning to a
sentence we generally try to avoid its use. The same applies to priority
claims such as ``the first'' that can also be difficult to verify
exhaustively. The description and interpretation of findings should be
able to convey the study's interest and importance. References should
not be cited in the Summary.

\subsubsection*{}

\subsubsection*{Keywords}

{\label{564595}}

Authors are encouraged to include up to ten keywords that will be
associated with the article on Cell Press platforms and on PubMed. These
keywords should be listed in the manuscript after the Summary separated
by commas.

\subsubsection*{}

\subsubsection*{Highlights}

{\label{263798}}

Highlights are a short collection of bullet points that convey the core
findings of the article. This list of points will be displayed online
with the Summary of the article but will not appear in
print.~\emph{Specifications}: up to four bullet points can be included;
the length of an individual bullet point should not exceed 85 characters
(including spaces); only the core results of the paper should be
covered.Highlights are required for all research papers and will be
displayed online with the article; however they will not appear in
print. On the EM page where you are asked to upload your files please
choose ``Highlights'' and upload a Word document including your
Highlights.

\section*{}

{\label{436567}}

\section*{Introduction}

{\label{352755}}

The Introduction should be succinct with no subheadings and should
present the background information necessary to provide a biological
context for the results.

\section*{}

{\label{333420}}

\section*{Results}

{\label{535346}}

This section should be divided with subheadings. Footnotes should not be
used.

\section*{}

{\label{368327}}

\section*{Discussion}

{\label{953704}}

The Discussion should explain the significance of the results and place
them into a broader context. It should not be redundant with the Results
section. This section may contain subheadings and can in some cases be
combined with the Results section.

\subsubsection*{}

\subsubsection*{Author Contributions}

{\label{155764}}

For primary research papers we ask you to include a dedicated Author
Contributions section preceding the Acknowledgments to give information
about individual author contributions to the work. Please keep this
section as concise as possible and use initials to indicate author
identity. All of the authors listed on the paper should be mentioned in
this section at least once. We are happy for you to use a traditional
format such as ``A.B. and C.D. conducted the experiments E.F. designed
the experiments and wrote the paper\ldots{}'' but would also encourage
you to
use~\href{http://www.cell.com/pb/assets/raw/shared/guidelines/CRediT-taxonomy.pdf}{the
CRediT taxonomy}~instead.

\section*{}

{\label{724055}}

\section*{Acknowledgments}

{\label{139503}}

This section may acknowledge contributions from non-authors and/or list
funding sources and it should include a statement of any conflicts of
interest.~Please check this section carefully as we cannot allow
amendments or corrections after publication.

\section*{}

{\label{947922}}

\section*{References}

{\label{470973}}

References should include only articles that are published or in press.
For references to in press articles please confirm with the cited
journal that the article is in fact accepted and in press and include a
DOI number and online publication date. Unpublished data submitted
manuscripts abstracts and personal communications should be cited within
the text only. Personal communication should be documented by a letter
of permission. Submitted articles should be cited as unpublished data
data not shown or personal communication.In-text citations should be
written in Harvard style and not numbered e.g. ``Smith et al. 2015;
Smith and Jones 2015.''Please use the style shown below for references.
Note that ``et al.'' should only be used after ten
authors.\textbf{Article in a periodical:}Sondheimer N. and Lindquist S.
(2000). Rnq1: an epigenetic modifier of protein function in yeast. Mol.
Cell~\emph{5} 163--172.\textbf{Article in a book:}King S.M. (2003).
Dynein motors: Structure mechanochemistry and regulation. In Molecular
Motors M. Schliwa ed. (Weinheim Germany: Wiley-VCH Verlag GmbH) pp.
45--78.\textbf{An entire book:}Cowan W.M. Jessell T.M. and Zipursky S.L.
(1997). Molecular and Cellular Approaches to Neural Development (New
York: Oxford University Press).

\subsubsection*{}

\subsubsection*{Figure Legends}

{\label{789718}}

Legends should be included in the submitted manuscript as a separate
section. Each figure legend should have a brief title that describes the
entire figure without citing specific panels followed by a description
of each panel. For any figures presenting pooled data the measures
should be defined in the figure legends (for example ``Data are
represented as mean \selectlanguage{ngerman}± SEM.''). Each legend should refer to any
supporting items in the Supplemental Information (e.g. ``See also Figure
S1.'').

\subsubsection*{}

\subsubsection*{Tables}

{\label{665788}}

When creating a table please use the Microsoft Word Table function.
Tables should include a title and footnotes and/or legend should be
concise. Include tables in the submitted manuscript as a separate
section. Tables not created with the Microsoft Word table function will
need to be revised by the author.When creating tables please adhere to
the following guidelines:

\begin{itemize}
\tightlist
\item
  Do not submit tables in Excel or PDF format. Do not place an Excel
  table in a Word document.~
\item
  Format tables with Word's Table function; do not use tabs or spaces to
  create a table.~
\item
  Tables should be in black and white; rows and columns should not be
  shaded.~
\item
  Do not use line breaks or spaces to separate data within a cell. Use
  separate cells for all discrete data elements within a table.~
\item
  Number tables as Table 1 Table 2 Table 3 etc. rather than as Table 1a
  Table 1b Table 1c etc.~
\item
  If bold or italic font is used within a table to indicate some feature
  of the data please give an explanation of its usage in the legend.~
\item
  All abbreviations within a table must be defined in the table legend
  or footnotes.~
\item
  Footnotes should be listed with superscript lowercase letters
  beginning with ``a.'' Footnotes may not be listed with numbers or
  symbols.~
\end{itemize}

\subsubsection*{}

\subsubsection*{STAR Methods}

{\label{521641}}

The STAR Methods section replaces our Experimental Procedures and
Supplemental Experimental Procedures sections. The STAR Methods section
should include enough detail to allow the reader to understand the
experimental design and to be able to assess the conclusions. STAR
Methods also detail what resources and procedures are needed for readers
to reproduce experiments using standardized sections and a Key Resources
Table. For guidelines on how to structure your paper in the STAR Methods
format please visit
our~\href{http://www.cell.com/star-authors-guide}{STAR Methods web page
for authors}. We encourage but do not require authors to follow the STAR
Methods format when articles are initially submitted. If accepted
articles must adhere to the STAR Methods format. Please see
our~\href{http://www.cell.com/cell/fulltext/S0092-8674(16)31072-8}{Editorial}
as well as the~\href{http://www.cell.com/star-methods}{STAR Methods
launch site} to learn how STAR Methods helps align our papers to
external reporting guidelines to improve transparency and robust and
rigorous reporting of methods details.

\subsubsection*{}

\subsubsection*{Supplemental Information}

{\label{250940}}

In general Supplemental Information is limited to data and other
materials that directly support the main conclusions of a paper but
cannot be included in the main paper for reasons such as space or file
format restrictions. SI should not be used to present data that are
preliminary or that conceptually go beyond the main point of the
paper.Before submitting your supplemental materials please refer to our
complete instructions in
the~\href{http://www.cell.com/cell/supplemental-information}{Supplemental
Information guidelines}. This page also contains information on
submitting movie and other multimedia files.

{}

\subsection*{Figures and Graphical
Abstracts}

Digital figure files submitted
through~\href{http://www.editorialmanager.com/cell/?__hstc=25856994.342f4a38a8d67c00d422f39bcee5d02a.1493747133689.1493747133689.1493747133689.1\&__hssc=25856994.1.1493747133689\&__hsfp=2247791852}{Editorial
Manager}~must conform to
our~\href{http://www.cell.com/figureguidelines}{digital figure
guidelines}~or authors will be asked to revise them.If you have any
questions about digital files please contact Trina Arpin Managing Editor
of~\emph{Cell} at~{tarpin@cell.com}.~

\subsubsection*{}

\subsubsection*{Graphical Abstract}

{\label{255753}}

A graphical abstract should allow readers to quickly gain an
understanding of the main take-home message of the paper and is intended
to encourage browsing promote interdisciplinary scholarship and help
readers identify more quickly which papers are most relevant to their
research interests. Examples of this feature can be seen in the online
version of articles published in~\emph{Cell}~from January 2010 onwards.
Graphical abstracts may be submitted at any stage but are only required
once a paper has been accepted for publication (it is not necessary to
provide a graphical abstract for a new submission). Graphical abstracts
can be uploaded
in~\href{http://www.editorialmanager.com/cell/?__hstc=25856994.342f4a38a8d67c00d422f39bcee5d02a.1493747133689.1493747133689.1493747133689.1\&__hssc=25856994.1.1493747133689\&__hsfp=2247791852}{Editorial
Manager}~by selecting ``Graphical Abstract'' when uploading files.~Refer
to our~\href{http://www.cell.com/figureguidelines}{digital figure
guidelines}~for graphical abstract preparation details.

{}

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