While the cattle industry has gone through great measures to improve herd management, animal facilities and care, feeding and nutrition, and appropriate use of bio-pharmaceutics, calf diarrhea still remains a problem due to its multifaceted nature (Bendali et al., 1999; Scott et al., 2004). Prevention and control strategies of diarrhea in young calves is based on a proper understanding of the disease complexities such as multiple pathogens, co-infection, environmental factors, feeding and management during the calving period.