IntroductionConsciousness refers to the state in which a person is awake and aware. The depth of wakefulness can be measured by Glasgow coma scale (GCS). Awareness is ability of responding appropriately to internal and external stimuli (1, 2). Consciousness state divides into coma (a pathologic state without wakefulness or awareness), vegetative state (unresponsive wakefulness syndrome), and minimally conscious state (1, 3).There is a broad spectrum of disorders that can cause stupor and coma. They are divided to two main groups: structural and functional pathologies. Structural etiologies include trauma and cerebrovascular disease. Nonstructural etiologies are intoxications, infections, seizures and metabolic derangements (4). Some of these differential diagnoses are emergencies such as acute stroke, expanding mass lesion, and herniation syndrome especially when there is papilledema or focal neurologic deficits in physical examinations and we can exclude them by head CT scan. Another emergency condition is bacterial meningitis and viral encephalitis presenting with fever. Thus, febrile unconsciousness suggest LP and further CSF evaluation (5). As mentioned above, metabolic derangements (such as hypoxia, hypoglycemia, hypernatremia, diabetic ketoacidosis, uremia, and hypothyroidism), toxins (including lead, cyanide, methanol, and carbon monoxide) and drugs (such as sedatives, barbiturates, opiates, alcohol, anticholinergics, H1-antihitamines, and amphetamines) could also result in decreased level of consciousness (6, 7).An important cause of decreased level of consciousness is drug intoxication, unintentional or deliberate poisoning. Deliberate self-poisoning is the most common way of suicide that leads to death or some substantial consequences like cardiac, brain, pulmonary, renal injury and other organ dysfunctions (8-10).Herein, we report a 25-year-old woman presented with steady unconsciousness (GCS=7) for 10 days.