Hi reddit, I’m Hilary Lawson - post-realist philosopher, director of the Institute of Art and Ideas and founder of the world’s largest philosophy and music festival HowTheLightGetsIn. Born and raised in Bristol, England, I was awarded a scholarship to study PPE at Balliol College Oxford . As a post-graduate I came to see paradoxes of self-reference as the central philosophical issue and began a DPhil on The Reflexivity of Discourse. This later became the basis for my first philosophical book Reflexivity: The Post-Modern Predicament. Alongside my more philosophical writing, I also pursued a media career following my studies. Within a few years I had created my own prime time television series ‘Where There’s Life’ with a weekly UK audience in excess of ten million. In 1982, I went on to co-author a book based on the series and was appointed Editor of Programmes and later Deputy Chief Executive at the television station TV-am. Meanwhile I continued to develop my philosophical thinking and had initial sketches of the theory later to become Closure. In 1985 I wrote Reflexivity: The Post-Modern Predicament as part of a series on modern European thought. In the book, I argued that the paradoxes of self-reference are central to philosophy and drive the writings of Nietzsche, Heidegger and Derrida. In the late 1980s I founded the production company TVF Media which made documentary and current affairs programming, including Channel 4’s flagship international current affairs programme, The World This Week. I was editor of the programme, which ran weekly between 1987 and 1991. The programme predicted the fall of the Berlin Wall, the war in Yugoslavia and the Iraqi invasion of Kuwait, amongst its other laudable achievements. In the 1990s, I focused on writing Closure. It took a decade to complete and was published in 2001. The book has been described as the first non-realist metaphysics. Having begun my philosophical career as a proponent of postmodernism, latterly I became a critic arguing for the necessity of an overall framework and the need to move on from a focus on language. Closure proposes that the human condition is to find ourselves on the cusp of openness and closure. The world is open and we, along with other living organisms, are able to apprehend and make sense of it through the process of closure. I would define closure as the holding of that which is different as one and the same. Human experience is seen to be the result of successive layers of closure, which I consider to be preliminary, sensory and inter-sensory closure. The highest level of closure, inter-sensory closure realises language and thought. The theory shifts the focus of philosophy away from language and towards an exploration of the relationship between openness and closure. An important element of the theory of closure is its own self-referential character. I founded the Institute of Art and Ideas in 2008 with the aim of making ideas and philosophy a central part of cultural life. Our website IAI.tv, which posts to the sub, was launched in 2011. We then moved to publishing articles in 2013 and free philosophy courses on IAI Academy in 2014. Links of Interest: Tickets and lineup for HowTheLightGetsIn 2018 can be found here - discounts available for students and U25s. Routledge has partnered with the IAI to offer a generous 20% off all their philosophy books and a free giveaway each month. Click here for details. After the End of Truth: A debate with Hannah Dawson (KCL) and John Searle (Berkeley) on objective truth and alternative facts What Machines Can’t Do | Hilary Lawson in debate with David Chalmers (NYU) and cognitive scientist and sex robot expert Kate Devlin (Goldsmiths) on the question of machine minds After Relativism: A debate on the pitfalls of relativism and potential solutions with Simon Blackburn and Michela Massimi
Hi everyone, happy to be here! Hyperhidrosis is a common condition, approx 3% of people deal with excessive sweating from their armpits, palms or soles of feet. It can be debilitating, the sweating is often heavy and uncontrollable, causing people to really struggle in social and work situations. The good news is that hyperhidrosis is highly treatable. At the Columbia Hyperhidrosis Center, our team of thoracic surgeons and dermatologists developed a multidisciplinary approach to the management of hyperhidrosis. While surgery is extremely effective at eliminating hyperhidrosis, there may be some unavoidable side effects, so we believe non-surgical options should be tried first. Here’s a little bit more about me and an interview about hyperhidrosis. Here’s my proof Edit: Thank you Reddit, I’ve enjoyed answering your questions. I’m signing off for now, and will try to check back in later today. Happy holidays!
Hello Reddit! My name is Tom Pering and I am currently a Teaching Associate at the University of Sheffield. My research focuses on the gases which volcanoes release. In particular, I am interested in volcanoes which have basaltic magmas. This type of magma allows the constant release of gases at the surface, which can then be measured using remote sensing techniques. As part of this, I am also interested in the modelling of how gas behaves within magmas, which then leads to a range of volcanic activities; such as strombolian eruptions. The research group in volcano remote sensing at the University of Sheffield has a strong history of developing such techniques. Recently we have developed a low-cost ultraviolet camera approach to remotely sense the volcanic gas sulphur dioxide (SO2), which incorporates the popular Raspberry Pi platform. Happy to answer questions about my research and more broadly about volcanology! Here are a few example papers from our recent research: Ultraviolet Imaging with Low Cost Smartphone Sensors: Development and Application of a Raspberry Pi-Based UV Camera - http://www.mdpi.com/1424-8220/16/10/1649 A Low-Cost Smartphone Sensor-Based UV Camera for Volcanic SO2 Emission measurements - http://www.mdpi.com/2072-4292/9/1/27 The dynamics of slug trains in volcanic conduits: evidence for expansion driven slug coalescence – http://www.sciencedirect.com/science/article/pii/S0377027316304267 Hello everyone! I am taking a break for a couple of hours but will keep an eye on this and return to answer questions at about 8 pm GMT (3 pm Eastern Time).
Hello Reddit! We are PhD student Noam Brown and Professor Tuomas Sandholm at the Computer Science Department of Carnegie Mellon University. We do research on developing AIs that can reason about hidden information (which is widespread in real-world strategic interactions). Earlier this year we built Libratus, the first and only AI to defeat top humans in no-limit poker. We played four of the world’s best pros in a 120,000 hand, 20-day Brains vs. AI match of heads-up no-limit Texas hold’em, with a prize pool of $200,000. The AI won the match decisively, winning a combined $1.8 million (at $50/$100 blinds). The victory was statistically significant with a p-value of 0.0002. The details of the bot were just published in Science Magazine! We’re here to talk about Libratus, the competition, what this means for the future of AI, and any other questions you might have. We’ll be back at 9 am to answer your questions, Ask us anything! EDIT: We’re closing the AMA. Thanks for the questions everyone!
Hi! I’m Daniel Blumenthal, a Professor of Electrical and Computer Engineering specializing in optical communications and photonic integration at the University of California – Santa Barbara, Fellow of the National Academy of Inventors, The Optical Society (OSA) and of the IEEE. Today’s high-speed optical communications technologies work to accelerate the way we work, live and play by connecting people and computers around the world over high speed communication pipes. My lab develops new hardware and communications technologies to solve complex communications, transmission, switching and signal processing problems out of reach with today’s technologies. The primary undertaking of our research is to develop new functions integrated on small chips called photonic circuits, and use these circuits to build networks in ways that save energy and increase the scale of connectivity and bandwidth of data centers and the Internet. We are, in theory, greening future networks while allowing them to scale to accommodate future applications and the systems that rely on those networks. I am a Professor in the Department of Electrical and Computer Engineering at the University of California, Santa Barbara and Director of the Terabit Optical Ethernet Center (TOEC) and head of the Optical Communications and Photonic Integration (OCPI) group (ocpi.ucsb.edu). I have served as PI for large-scale research programs including DARPA/MTO funded CSWDM, LASOR and iPhod projects at UCSB. In addition, I have served on the Board of Directors for National LambdaRail (NLR) and Internet2 Architecture Advisory Council. I have co-founded two companies, Packet Photonics, Inc and Calient Networks. My research interests are in optical communications, photonic packet switching and all-optical networks, ultra-low loss optical waveguides and silicon nitride photonics circuits, all-optical wavelength conversion and regeneration, ultra-fast communications, InP Photonic Integrated Circuits (PICS) and nanophotonic device technologies. I have published over 410 journal and conference papers, 5 book chapters, and co-authored a leading book on tunable lasers. I have served on technical program committees of international conferences including the conference on Optical Fiber Communications (OFC) and as guest editor for multiple journal special issues. I will be back at 1 pm ET to answer your questions, and I look forward to sharing with you today. Feel free to Ask Me Anything!
Hi Reddit! This is Johna Leddy, president of The Electrochemical Society (ECS). I’m joined by Jeff Fergus, editor of the Society’s official meeting proceedings, ECS Transactions (ECST). Today we’d like to talk with you all about open science, our Free the Science initiative, and our new preprint server, ECSarXiv, built and hosted by the Center for Open Science’s Open Science Framework. We’ll be back at 12 noon ET to answer your questions, ask us anything! ECS Chief Content Officer & Publisher Mary E. Yess (username: ecspublisher) will also help to field questions. More about us: Dr. Johna Leddy: I’m an associate professor of chemistry at the University of Iowa, an alumna of Rice University and the University of Texas, and the current president of ECS. I’ve been an ECS member for over 25 years and have served on various committees within the organization. I’m also a former chair of ECS’s Physical and Analytical Electrochemistry Division. My research interests range from fundamental electrochemistry through voltammetric methodologies and modeling to the technology of power sources. A major focus for me has been examining magnetic effects on electron transfer processes. Dr. Jeff Fergus: I’m a professor of materials engineering and the associate dean for program assessment and graduate studies in the Samuel Ginn College of Engineering at Auburn University. I’ve served as the editor of ECST, ECS’s official meeting proceedings, since 2013. I’ve also held positions on multiple committees within the organization and served as the chair of the ECS High Temperature Materials Division. My research interests are in materials for high temperature and electrochemical applications—particularly in understanding and mitigating performance degradation, such as chromium poisoning in SOFCs and capacity fading in Li-ion batteries. The Electrochemical Society (ECS): ECS is a nonprofit scientific society that has been publishing continuously since 1902. We’re an international membership organization that has over 8,000 members worldwide across more than 80 countries. Our mission is to disseminate and advance the science we steward through meetings and publications, and we believe the best way to do that is through transition to an open science paradigm. This mission is the driving force behind our Free the Science initiative: www.electrochem.org/free-the-science. We believe that by opening and democratizing research, we can enhance and accelerate the science that will ensure our survival and sustainability on this planet. We already give authors the opportunity to publish open access in our 2 peer-reviewed, hybrid open access journals—the Journal of The Electrochemical Society and the ECS Journal of Solid State Science and Technology. Currently, over a third of our journal articles are being published open access. The upcoming launch of ECSarXiv will mark a major step forward for Free the Science toward the complete open access model we plan to one day implement, allowing all authors to publish for free and removing the paywall for readers. We invite anyone who wants to know more about open science, Free the Science, preprint servers, or scholarly communications to ask questions here. For more info about us, check out our website at www.electrochem.org. Edit: Thanks, everyone, for the insightful questions and discussion. That’s all the time we have today. We had a great experience talking with you all—you raised a number of excellent points about the open science movement that we’ll want to keep in mind as we move forward. Until next time, please feel free to reach out to us with questions at email@example.com.
Under the goals of the 2015 Paris climate agreement, the world has agreed to do what is needed to keep global temperatures from not rising above 2°C as compared to pre-industrial levels. According to the International Panel on Climate Change, in every economically viable scenario to that goal requires reaching zero emissions and requires the deployment of carbon-capture technologies on large scale. These technologies allow us to keep burning fossil fuels almost without emissions, while putting us on the trajectory to hit our climate goals. They are considered a bridge to a future where we can create, store, and supply all the world’s energy from renewable sources. But carbon-capture technologies have a tortured history. Though first developed nearly 50 years ago, their use in climate-change mitigation only began in earnest in the 1990s and scaling them up hasn’t gone as planned. My initial perception, based on what I had read in the press, was that carbon capture seemed outrageously expensive, especially when renewable energy is starting to get cheap enough to compete with fossil fuels. At the same time, my training in chemical engineering and chemistry told me the technologies were scientifically sound. And some of world’s most important bodies on climate change keep insisting that we need carbon capture. Who should I believe? The question took me down a rabbit hole. After a year of reporting, I’ve come to a conclusion: Carbon capture is both vital and viable. I’ve ended up writing nearly 30,000 words in The Race to Zero Emissions series for Quartz. You can read the 8,000-word story where I lay the case for the technology here: https://qz.com/1144298; other stories from the series here: https://qz.com/re/the-race-to-zero-emissions/; and follow the newsletter here: https://bit.ly/RacetoZeroEmissions. I’ll be back at 11 ET (16 UTC) to answer questions. You can ask me anything! Bio: Akshat Rathi is a reporter for Quartz in London. He has previously worked at The Economist and The Conversation. His writing has appeared in Nature, The Guardian and The Hindu. He has a PhD in organic chemistry from Oxford University and a BTech in chemical engineering from the Institute of Chemical Technology, Mumbai. 1 ET (18 UTC): I’ve answered all the questions. Thanks for having me!
Welcome to our new semi-regular Science Issues Discussion. This month, the discussion topic is net neutrality and potential impacts on science, science communication, education, and and informed citizenry. Some example concerns are: How will this impact scientists’ abilities to collaborate on projects? How will this impact citizen science initiatives? Will this exacerbate the relationship between income levels and access to scientific knowledge? How will this impact science communication and journals - especially open access journals? How will this impact start-ups and smaller private scientific enterprises? To guide us in this discussion we have invited Ryan Singel (u/ryansingel2) who is a Media and Strategy Fellow at Stanford Law School and represented start-ups at a meeting with then FCC chairman Tom Wheeler about net neutrality. Ryan Singel covered net neutrality (and more) for Wired from 2002 to 2012. He left Wired to found Contextly, an engagement platform for publishers. He’s now a Media and Strategy Fellow at Stanford Law School’s Center for Internet and Society focussing on net neutrality and the CEO of Contextly. You are welcome to ask Ryan questions directly but we also invite him to engage with ongoing discussions where he can lend his expertise and share his thoughts. Science Issue Discussions are more relaxed formats than AMAs. We encourage you to bring your own personal experience - especially those of you who have flair in our sub and can speak to how this topic impacts your own field of study. Anecdotes and personal narratives are permitted. However, we still maintain strict rules about commenting and we do not permit rudeness, hateful or angry comments, bigotry, doxing, or witch hunts. Your comments should be related to the topic of the discussion and not jokes, memes, or pop culture references. No pseudoscience and this is not the place for grandstanding or big political arguments. Failure to adhere to these rules will have your comments removed and you risk being banned.
First and foremost, full disclosure: I am the CEO of Posit Science, which is a company that develops BrainHQ, a brain training program. I joined Posit Science at its inception because I believed it was essential to form a company to help the basic science of brain plasticity become an applied science that could improve human lives. I am also a neuroscientist by training, earning my Ph.D. from UCSF in the lab of recent Kavli Prize Laureate Dr. Michael Merzenich, who was (and still is!) a pioneer in the discovery and characterization of adult brain plasticity. You may have seen his recent AMA here. Today, join me to talk about a recent paper – hot off the (digital) press – showing that speed of processing training – a specific type of brain training – uniquely and significantly reduces the risk of healthy adults going on to dementia. This is the first randomized controlled trial of any intervention – pharmaceutical, physical exercise, mindfulness, or nutrition – to show an effect on the risk of dementia. These results come from the ACTIVE study, an NIH-funded multi-site trial, and is authored by independent researchers, including Drs. Jerri Edwards and Fred Unverzagt from the University of South Florida and Indiana University. I’ve worked with both Dr. Edwards and Dr. Unverzagt, and I’m very familiar with the ACTIVE study in general and these results in particular. Check out the paper here and ask me anything! About the ACTIVE study, dementia, the field of brain training as a whole, what near transfer/far transfer/generalization really means, my favorite aspects of clinical trial design and analysis (handling missing data, of course), brain plasticity, and video games. Or take a left turn and ask me about being ranked silver in Overwatch (the struggle is real), your and my favorite vermouths and amari, what it’s like to go from academia to the private sector, and the best burrito in San Francisco. Proof Edit: Hi folks - thanks for all the great questions about brain training - how it works, what’s been shown, and who it can help. It was really fun to talk about these issues with you. I’ll keep an eye on the AMA for the rest of today and tomorrow, and answer any further questions that get posted.
Hello, Reddit! My name is Aydogan Ozcan, and I am currently a Chancellor’s Professor at UCLA, in Electrical & Computer Engineering, and Bioengineering. I am also an HHMI Professor at the Howard Hughes Medical Institute, an Associate Director of the California NanoSystems Institute, and a Fellow of SPIE, IEEE, OSA, AIMBE, RSC and the Guggenheim Foundation. My research focuses on the use of computation/algorithms to create new optical microscopy, sensing, and diagnostic techniques, significantly improving measurement existing tools for probing micro- and nano-objects while also simplifying the designs of these analysis tools. Some examples include smartphone-based microscopes, cell counters, diagnostic test readers, bacteria sensors, blood analyzers, allergen detectors, heavy metal sensors among others. I have authored, and will be presenting, multiple papers on these technologies at SPIE Photonics West in February 2018. More information about this conference can be found here. Let’s get the discussion started. I’ll be back at 2 pm Et to answer your questions, Ask me anything
ACS AMA Hi Reddit, I’m Terri Woods! I am an Associate Professor of Geological Sciences at East Carolina University (ECU). In 1971 I entered the University of Delaware with the goal of teaching high-school Spanish. Instead I became fascinated by how things work in the geological world and changed my major. While working on an MS at Arizona, I worked for the Anaconda Copper Company in Tucson and did mineral exploration with them in Montana. My thesis involved microprobe and fluid-inclusion work on a garnet skarn. I interviewed with mining/oil companies but got turned off by comments from interviewers such as; “We are looking for a few good gals”. Luckily, I got another offer from the USGS in Reston, Virginia to work on the epithermal sulfide deposit at Creede, Colorado. I worked there for 3 years but my husband and I got tired of the DC area and went cruising on our 43-foot wooden sailboat. We ran out of money in St. Petersburg, Florida at a time when geology employment was hard to come by so I worked minimum-wage jobs until Bob Garrels (USF-Marine Science) asked me to run his lab. For the next 5 years I helped Bob with projects such as copper corrosion in sulfate, carbonate and chloride solutions; water chemistry in equilibrium with Australian BIF; C and S cycling through geological time, and compilation of thermodynamic data. I got my Ph.D. in 1988. That fall I started as a faculty member at ECU. I did lab work on copper corrosion, but students were into hydro-environmental studies so I began investigating the chemistry of water from local aquifers. That research continues, but I have also worked on the impact of reverse-osmosis brine discharge into Albemarle Sound, chemistry of nearby streams, and petrology of aquifer materials. I’ve devoted a lot of time to science outreach. Most recently, I have investigated a technology that helps people understand surficial processes and topographic maps - the Augmented Reality Sandbox: short demo video https://mediasite.ecu.edu/MS/Play/ba30d1a13a684667ab155bfa58fd782a1d longer educational video https://mediasite.ecu.edu/MS/Play/e579f009dbca41e79f0d84d7207a714a1d This past spring (2017), I was happy to serve as the scientific consultant for the ACS Reactions video “Why is the Statue of Liberty Green?” https://www.youtube.com/watch?v=_ZSLrXtg1-o So, Reddit, ask me anything about aqueous geochemistry, copper corrosion, or using augmented reality to teach surface geology. I’ll be back to start answering your questions at 12pm EST (9am PST; 5pm UTC).
Hi, we’re NASA engineers working on space communications technologies that will help create an interplanetary internet. When data travels vast distances like the 30+ million miles to Mars, the potential for delay or disruption is significant! Network disruption in space can happen because of limited contact time and atmospheric effects. NASA communications technology called ‘disruption-tolerant networking’ (DTN) allows for temporary disruptions and long delays, unlike the familiar computer to computer IP connection. DTN can also provide tremendous benefits to missions closer to Earth and terrestrial applications. That’s what we’re working on, and it has the potential to improve data transmission for virtually all of NASA’s missions. We are: Vint Cerf, Distinguished Visiting Scientist, NASA’s Jet Propulsion Laboratory Dave Israel, Exploration and Space Communications Architect, NASA’s Goddard Space Flight Center Adam Schlesinger, Technical Lead, Advanced Exploration Systems Delay/Disruption Tolerant Networking Project, NASA’s Johnson Space Center Scott Burleigh, Principal Engineer, NASA’s Jet Propulsion Laboratory Kelvin Nichols, International Space Station ground systems engineer, NASA’s Marshall Space Flight Center Dr. Keith Scott, The MITRE Corporation For more information on disruption-tolerant networking, visit: https://www.nasa.gov/content/dtn Don’t forget to follow us on Twitter at @NASA_TDRS, @NASALasercomm and @NASASCaN!
The mods of /r/philosophy are pleased to announce an upcoming AMA by Rivka Weinberg, Professor of Philosophy at Scripps College, who works on procreative ethics, bioethics and the metaphysics of life and death. She is the author of The Risk of a Lifetime: How, When, and Why Procreation Might Be Permissible (OUP, 2015). Professor Weinberg will be joining us on Monday November 27th at 1PM EST to discuss issues in procreative ethics, bioethics and more. Hear it from her: Rivka Weinberg I’m Professor of Philosophy at Scripps College, which is one of the Claremont Colleges, in way too sunny California. I grew up in Brooklyn (before it was cool), worked my way through Brooklyn College as a paralegal, and got my PhD. from the University of Michigan, in Ann Arbor. Most of my philosophical work has focused on the ethics and metaphysics of creating people. It still surprises me that so many people just go ahead and create an entire new human without really thinking through what they are doing to that person. It surprises me even more that so many people seem to think that life is inherently good and that living is a privilege and a treat. I find that outlook very hard to understand, though I haven’t given up trying. My book, The Risk of a Lifetime: How, When, and Why Procreation May Be Permissible, is a culmination of my many years of thinking about what we are doing when we create a person. As the title reveals, I think we are imposing life’s risks on that person, and I consider when and why that set of risks may be permissible to impose. Although it might seem foreign to think about having a baby as imposing life’s risks on someone, I don’t think it’s as counterintuitive a conception of procreation as it might initially seem. It’s not odd to think that a teenager shouldn’t have a baby because that baby will have lots of disadvantages, i.e., face the high degree of significant life risks that are associated with being born to teen parents. It’s not unusual to think that people who carry genes for terrible diseases, such as Tay Sachs, should try to make sure that they don’t partner with another carrier and bear a child who will have to suffer so terribly. Many people think that they shouldn’t have children who would be at a high risk for a life of abject poverty. And those are all ways of thinking about whether the life risks we impose on those we create are permissible for us to impose. So that is my framework for thinking about procreative ethics. Within that framework, I think about what kind of act procreation is, whether it is always wrong, whether metaphysical puzzles such as Parfit’s famous non-identity problem make it almost always permissible (short answer: so not!), and what makes someone parentally responsible. In my book, I arrive at principles of procreative permissibility based on a broadly contractualist framework of permissible risk imposition. I am currently finishing up some papers on whether parental responsibility has a set endpoint, or indeed any endpoint; and on some aspects of risk imposition that are unique to, and uniquely problematic for, procreative acts. I am also thinking a lot about pointlessness, about how life is not the kind of thing that can have a point or purpose, and whether we can rationally find that disappointing or even tragic. I probably should have thought that through before I had children who now have to live pointless lives, like everyone else. Ah well. Fun fact: I have two children, and ten siblings. Links of Interest: Her book: The Risk of a Lifetime: How, When, and Why Procreation Might Be Permissible An article reviewing David Benatar’s antinalist book (Better Never to Have Been: The Harm of Coming Into Existence): “Is Having Children Always Wrong?” NewBooksNetwork podcast interview on her book “The Moral Complexity of Sperm Donation” Short piece in Quartz: “Is it unethical to have children in the era of climate change?” Another short piece in Quartz: “When is it immoral to have children?” AMA Please feel free to post questions for Professor Weinbreg here. She will look at this thread before she starts and begin with some questions from here while the initial questions in the new thread come in. Please join us in welcoming Professor Rivka Weinberg to our community!
Hi Reddit! I’m Judy Baumhauer, a professor of Orthopaedics at the University of Rochester and medical director of PROMIS, a computerized assessement system that captures and tracks patients’ perspectives on their care. I am an Orthopaedic surgeon, and medical director of the University of Rochester’s program to incorporate PROMIS across our entire medical system. Our goal is to invite every patient to share their perspective on the effectiveness of their health care so we can learn from patients, and improve the overall quality of care we deliver. PROMIS is a National Institutes of Health-sponsored system that was developed at Northwestern University. It’s been shown to be a very accurate way to measure how well a patient is progressing. The system asks patients a variety of questions on their pain, physical function, and state of mind, or mood, to assess their health care outcomes. It uses smart testing and asks the following question based on the answer to the prior question. This way the patient does not get the same set of questions at the next patient visit. At the University of Rochester, 30 programs use PROMIS in their outpatient clinics and more programs are continuing to adopt it. We offer the assessment at every outpatient visit and participation is voluntary for patients. We hand patients a tablet when they check in for their appointment, and they spend less than 3 minutes answering multiple-choice questions about their pain level, mood, and ability to manage everyday tasks like walking, exercise and housework. When patients complete the survey, their scores go into their health record, and their health team can view that day’s results – plus their previous scores– on a computer before or during the patient appointment. Health teams use the patient input to assess how an individual patient is progressing; collectively, the data can yield insights on the benefits of particular therapeutic approaches. Patients’ input on what worked for them – and what didn’t – is building a kind of health care “trip advisor.” But rather than being an online reference for other patients, this tool will be a road map for health providers as they seek the best care pathways for future patients. Many health care organizations around the world are interested in the potential for patient-reported health assessments, but it can be challenging to add this activity to clinical environments that are already very busy. UR is one of the world leaders in designing a system that works well in a clinical setting, and puts patient insights to work in improving care. We’ve been benchmarked by academic medical centers from the U.S., Europe and Asia who are working to adopt PROMIS in their clinical environments. I’ll start answering questions at 1 p.m. EDT. AMA!
The Society of Environmental Toxicology and Chemistry (SETAC) is hosting the SETAC North America 38th annual meeting this week and we have tied this AMA to a specific session, “Pharmaceuticals in the environment: Potential environmental and human health impacts.” Experts from across academia, government and industry are here to answer questions on this topic. The research being presented at our meeting will cover topics such as how fish react when a variety of medicines get through wastewater treatment and into their environment, to what levels of detection in water is risky to human health, to how veterinary medicines given to cattle get into the environment, among others. Please do note that we are asking members of the society who represent researchers from a variety of disciplines and sectors; the answers are not official SETAC positions. We encourage discussion and debate! Just please keep it professional. For more information on SETAC see http://www.setac.org Post your question and the organizers of the conference will find someone to answer it as soon as possible. Answers to questions will be most active during the session break at 10AM-11AM EST and immediately following 12PM-2PM EST, ending at 2PM EST.
ACS AMA Hello Reddit, my name is Aaron Wheeler. I am Professor of Chemistry (with a cross-appointment in Biomedical Engineering) at the University of Toronto. I also serve as Associate Editor of Lab on a Chip, and am a recent recipient of the Pioneers of Miniaturisation award. I received my B.S. from Furman University in 1997, and Ph.D. from Stanford University in 2003. After a postdoctoral fellowship at UCLA, I began my faculty career at the University of Toronto in 2005. My research interests are in the area of microfluidics – the study (and application) of fluid flow on devices with features in the micrometer-length-range. The technology was popularized in the early 1990s for miniaturized chemical separations, but in the intervening years it has been applied to an incredible array of applications, ranging from genomics and synthesis to music and mazes. The international community of researchers who work in this area is large and diverse, including thousands of chemists, physicists, biologists, engineers, medical professionals, and more. Each year, I look forward to participating in international conferences such as MicroTAS – I am always amazed by the ever-growing list of applications for the technology. Like many of my colleagues in the microfluidics community, I am interested in building portable, hand-held analysis systems that may someday contribute to efficient, inexpensive healthcare delivery (see a short movie illustrating this idea). Portable diagnostics are particularly attractive in remote settings with limited resources, and in fact, my research group recently returned from a field trial of our technology in Kakuma Refugee Camp in northwest Kenya (see a short movie about the trip). These types of projects and goals are much larger than what one group (alone) can accomplish; thus, my team and I are proponents of the “maker,” “hacker,” and “open source” movements in scientific research (see our review in Analytical Chemistry about this idea). Well, Reddit, I look forward to our discussion. Ask me anything about microfluidics and related topics starting at 11am EST (8am PST, 4pm UTC).
Hi Reddit, my name is Seth Blackshaw and I'm a professor of neuroscience at the Johns Hopkins University School of Medicine. My research focuses on identifying the network of genes that controls how different cell types in the hypothalamus are specified during embryonic development, and on using these findings to both identify how specific cell types regulate behavior and determine how they can be replaced in neurodegenerative disease. I became interested in this work because I am convinced that to understand how neural circuits work, we have to name and catalog their basic components -- the thousands of different cell types present in the brain. If we can figure out how these cell types are made, we can then understand which behaviors they regulate and how they do so. We study development of the hypothalamus because it is a master regulatory center for many interesting and medically important behaviors -- ranging from circadian timing to sleep to aggression. I recently published a paper on Nature describing newly identified brain cells in mice that play a major role in promoting sleep.. My team observed that a specialized type of neuron that had never been found in this area of the brain before appear to connect a part of the hypothalamus, called the zona incerta, to areas of the brain that control sleep and wakefulness. This discovery could lead to the development of new therapies to help people with sleep disorders, like insomnia and narcolepsy, which are caused by the dysfunction of similar sleep-regulating neurons. I look forward to answering your questions at 1pm ET
Hi Reddit, The mammalian immune system is fascinatingly complex. Our understanding of how the immune system recognizes and responds to foreign pathogens has increased tremendously in the last 100 years, however, we still have a great deal to discover. This point is highlighted by the recent discovery of a heterogenous family of tissue-resident lymphocytes (white blood cells) called innate lymphocytes (ILCs), which have been reported to regulate fundamental processes such as host metabolism, wound healing, and host defense. Given the importance of ILCs in these processes, my research focuses on the molecular and cellular signals that activate and sustain certain types of ILCs (Group 1 ILCs) in specific contexts. Understanding these mechanisms could have implications for the treatment of cancer, viral infection, and type II diabetes. While research from the past few decades has revealed that the immune system bridges virtually all physiological systems as a central regulator of host homeostasis, the general public (as well as scientists in other fields) only have vague ideas about immune function. Specialized jargon rampant in the field represents a barrier for the understanding of important advances in immunology, and for public consensus on its translation to the clinic (e.g. vaccination). Therefore, Immunologists need to make their work more accessible by presenting it in public forums and communicating their studies in a clear manner to try and eliminate these barriers. I think that Reddit AMAs present an excellent opportunity to highlight exciting findings in Immunology, and demystify academic science through informed discussion! I am happy to answer questions about the immune system, innate lymphocytes, and the implications for tissue-resident immunity in health and disease. I’m also happy to answer any questions about our most recent work http://www.cell.com/cell/fulltext/S0092-8674(17)31183-2. Edit 1: Hi all! I’ll start answering questions at 3pm ET!! Edit 2: Thanks again everyone for your excellent questions! Hopefully I have satisfactorily answered them. I’m signing off for now, but if you have further questions you can contact me through www.osullivanlab.com