Laryngeal injury is a life-threatening risk in contact sports. Exercise-induced laryngeal obstruction (EILO) can occur as a result of trauma. Athletes can return to monitored training within weeks of laryngeal surgery. Due to the rarity and complexity of laryngeal trauma in sport, effective management requires a multidisciplinary approach.
DS-ALL patients have a higher rate of relapse and treatment-related mortality. We describe a DS-ALL patient with late bone marrow relapse who was treated per British ALL R3 reinduction chemotherapy. The patient remained in remission for approximately two years after therapy was discontinued due to severe systemic infections.
A 13-month-old healthy patient without COVID-compatible symptoms and no known sick contacts presented to the emergency department with an esophageal coin. New institutional policy requiring pre-operative SARS-CoV-2 testing was positive for the virus. Additional precautions were taken in the operating room to successfully prevent transmission of the virus.
The atrial septal aneurysm is a rare cardiac abnormality that is usually detected during routine echocardiography or evaluation of cases with thromboembolism. We report a 62 years old male who presented with abdominal pain and bleeding per rectum found to have ischemic colitis and atrial septal aneurysm on transesophageal echocardiogram.
Background The theory of “hit and run” raises a possibility of novel COVID19-associated Parkinsonism cases, as well as worsening of symptoms in patients with pre-existing Parkinson’s Disease (PD). Aim/method To demonstrate that the COVID19 infection may lead to long lasting immunological and neurological changes at PD patients.
Abiotrophia defectiva (A defectiva), a rare cause of bacterial infective endocarditis(IE) often presents with pyrexia and florid sepsis. This case highlights that A defectiva IE can present non-specifically in older frail patients without classical clinical findings. A. defectiva may be associated with a high proportion of culture-negative IE.
Background Obesity is a chronic disease that is increasing in prevalence in adults, adolescents, and children and it is now considered to be a global epidemic. Current recommendation for treatment of Chronic Myeloid Leukemia (CML) does not take in consideration the weight of the patient and doses ofTKIs
A 51 yo man presented with weakness and constitutional symptoms, found on labs to have EJ-antibody antisynthetase syndrome. Myopathy is usually a late manifestation of Antisynthetase syndrome and is steroid-responsive, however in our case it occurred earlier. It is important to consider Antisynthetase syndrome in patients presenting with inflammatory myopathy.
Molecular targeted drugs and immune checkpoint blockades are not indicated for all advanced non-small cell lung cancer (NSCLC) cases. For such patients, cytotoxic drugs are the main treatment, and the prognosis remains poor. We present a valuable case of advanced NSCLC that was potentially permanent cured by pemetrexed maintenance chemotherapy.
Rasmussen's encephalitis is a rare chronic neurological disorder, characterized by unilateral inflammation of the cerebral cortex, drug-resistant epilepsy, progressive neurological and cognitive impairment. We report a case of a 17-year old male with persistent epilepsy, intellectual impairment, and cognitive deterioration.
A female with hemophilia had undergone bilateral total knee arthroplasty. She had a history of numerous hemorrhages. After further investigations, the diagnosis of von Willebrand disease type 2N confirmed. The von Willebrand disease, rare bleeding disorders, and severe platelet disorders are the differential diagnoses for hemophilia A
Kikuchi–Fujimoto disease (KFD) is a rare disease characterized by cervical lymphadenopathy, fever, and skin rash. The KFD can be confused with other conditions including lymphoma, autoimmune, and hematological diseases, which can lead to misdiagnosis of KFD as a clinical identity. Another condition can be novel coronavirus disease 2019 (COVID-19).
Optimal treatment for Philadelphia chromosome-positive mixed phenotype acute leukemia (Ph+ MPAL), particularly in elderly patients with comorbidities, has not been established. We present the elderly Ph+ MPAL case who discontinued initial treatment with dasatinib and whose disease was successfully controlled by low-dose imatinib with monitoring of drug concentrations in blood.