Cutaneous Leishmaniasis (CL) is often a localized and self-limited disease, but its behavior changes in the state of immunosuppression. Here, we report a rare clinical presentation of disseminated CL after reactivation of leishmania infection in a 42 year old male with corticosteroid induced immune suppression.
Typical form of Hemolytic Uremic Syndrome is caused most commonly enterohemorrhagic E. coli strain O157:H71. Here we report a unique case of HUS secondary to enteropathogenic E. coli infection, with a discussion on the diagnosis of HUS and how it is distinguished from other thrombotic microangiopathies (TMAs).
A 24-year-old male presented with radiating back pain and progressive neurological deficit. MRI revealed spinal epidural tumor at the thoracolumbar junction. He underwent decompression and excisional biopsy. Histopathology and immunohistochemistry identified it as diffuse large B-cell lymphoma. He received chemotherapy and is asymptomatic at one-year follow-up.
Epidermolytic hyperkeratotic EN (epidermal nevus) is a rare variant of EN, which can be congenital or developed later in adulthood. A 23 years old female presented with a pathologic confirmed epidermolytic hyperkeratotic EN. Dermoscopy can be helpful in the diagnosis of EN, but not in differentiating the variant.
In this report, we present a case of the Superficial circumflex iliac perforator-intercostal artery perforator (SCIP-ICAP) compound flap after extensive debridement of the upper extremity with necrotizing soft tissue infection (NSTI). There has been no previous report of the SCIP-ICAP compound flap applied for the upper extremity with NSTI.
Neuropsychiatric systemic lupus erythematosus (NPSLE) is usually associated with a worse prognosis. However, there are few effective treatments for NPSLE. We described protein A immunoadsorption treatment for a patient with NPSLE. The patient’s brain lesions was improved rapidly after two sessions of protein A immunoadsorption combination with immunosuppressive agent treatment.
Although parathyroid tissue auto-transplantation is useful for preventing hypoparathyroidism during thyroidectomy, hyperparathyroidism may occur due to proliferation of the transplanted parathyroid tissue. Hyperparathyroidism due to the autografted parathyroid gland should be suspected in patients who undergone parathyroid auto-transplantation.
Premature ovulation may occur during controlled ovarian stimulation. Usually, this is noticed and treatment is canceled before ovum pick up (OPU). In this case, a 24-year-old woman naturally conceived during the stimulation and OPU was successfully performed afterwards. Despite developing severe ovarian hyperstimulation syndrome, she delivered a healthy baby.
Retropharyngeal emphysema is a rare condition with various causes including traumatic and iatrogenic injuries, or it could occur spontaneously. Symptoms of mediastinitis and/or airway obstruction should be evaluated as indicators for surgical incision. Complications of mediastinitis are associated with poor prognosis; therefore, worsening of symptoms should be carefully monitored.
Blastic plasmacytoid dendritic cell neoplasm is a rare disease with difficulty in diagnosis, and clinical courses of patients with BPDCN vary widely. We report a case of a 63-year-old man with BPDCN showing severe tumor lysis syndrome (TLS). BPDCN with high tumor burden should be carefully considered to prevent TLS.
A patient with mucopolysaccharidosis type VI, on enzyme replacement therapy (galsulfase) for more than 6-years with good adherence. Urine glycosaminoglycans became stable, cardiopulmonary progression is slow, motor skills have improved, pain is controlled and no adverse reactions were reported. These support the benefits of galsulfase, as it slows disease progression.