Herein we report the intriguing case of a 42-year-old woman presenting with grade three hypertension, severe hypokalemia and primary amenorrhea, which revealed to be the complete form of 17 alpha-hydroxylase deficiency. We also discuss the challenging therapeutic approach as well as the outcomes and the follow-up of this patient.
Methemoglobinemia is a rare but fatal disorder of the oxygen-carrying capacity of hemoglobin. Here is a case representing high-dose Sulfamethoxazole/ Trimethoprim ( SMX/TMP ) induced Methemoglobinemia in a boy treated for Ventilator-associated pneumonia (VAP), which was resolved successfully after administration of methylene blue and discontinuation of SMX/TMP
Retroperitoneal sarcoma is relatively uncommon. We share our experience in encountering retroperitoneal sarcoma with vascular and urethral adhesion in a 46-year-old woman. Given the rarity of these tumors, evaluation and management should ideally be performed in a center equipped with multidisciplinary expertise in treating sarcomas.
A 55-year-old female patient presented with generalized tonic-clonic seizures. Laboratory evaluation showe low calcium (4.9 mg/dL), low PTH (0.9 pg/mL), & positive activating CaSR antibodies. The condition was diagnosed as autoimmune hypoparathyroidism. Vitamin supplements did not correct the patient’s hypocalcemia and steroids were added to the treatment.
Here we discuss a diabetic 54 years old female presented with malignant otitis externa and bilateral facial paresis followed by cervical spondylitis and C1-C2 instability. Skull base osteomyelitis confirmed by clinical presentation, imaging, and lab data. Fortunately, she responded well to anti-bacterial and antifungal therapy.
The use of Dynamic Movement Orthoses® is examined in a young woman with hypermobile Ehlers-Danlos syndrome (hEDS) referred for physiotherapy with hip dysplasia, prior to a right peri-acetabular osteotomy. Dynamic Movement Orthoses® plus rigorous subjective examination, therapists’ listening skills and patient-centred goals was useful for this hEDS patient.
Objective: To present 29-year-old patient with neurosyphilitic changes characterized by multiple acute ischemic brain strokes along with significant narrowing of several large intracranial arteries. After treatment of patient with ceftriaxone for 14 days following benzathine benzylpenicillin weekly for additional three weeks, meningovascular changes regressed.
Paraneoplastic syndrome is often not an obvious or common clinical presentation, but this report demonstrates that migratory arthropathies, may be the first presenting sign for non-small cell lung cancer (NSCLC). This study showcases an example of paraneoplastic syndrome, so other healthcare providers can be aware of early NSCLC manifestations.
Congenital dyserythropoietic anemias (CDA) is a heterogeneous class of anemia of varying degrees of ineffective erythropoiesis and secondary hemochromatosis. We reported a case of CDA and showed our approach to reaching a diagnosis, highlighting the importance of the typical morphological appearance of bone marrow erythroblasts to reach the diagnosis.
During pregnancy, liver cirrhosis and portal hypertension may worsen significantly, placing an increased risk of serious morbidity and life-threatening events. With the use of a wide variety of diagnostic tools and improved treatment strategies, women with liver disease in pregnancies are being diagnosed with significantly improved obstetric outcomes
Cardiac etiologies of hemoptysis are less common. One such etiology includes mitral regurgitation. In patients with hemoptysis and unilateral consolidation, mitral valve regurgitation should be considered, and careful chest auscultation and cardiac assessment may assist in making an early diagnosis.
Inflammatory granuloma caused by a vegetable foreign body is a lesion that can develop in the oral cavity. It results from the implantation of a vegetable, leading to an inflammatory reaction and the development of an aggressive osteolysis. This case highlights importance of clinicians' awareness regarding this uncommon disorder
SARS-CoV-2 infection can manifest many rashes. However, thrombotic retiform purpura rarely occurs during COVID-19 illness. Aggressive anti-COVID-19 therapy with a high-dose steroid regimen led to rapid recovery. This immuno-thrombotic phenomenon likely represents a poor type 1 interferon response and complement activation on the endothelial surface in response to acute infection.
Here we report a patient with 2q37 deletion syndrome confirmed by comparative genomic hybridization (CGH) plus single nucleotide polymorphism (SNP), who does not suffer from mental developmental abnormalities. The patient, however, does suffer from fatigue and gross motor delay, and the presence of a patent foramen ovale.
Internal hernias represent only 0.5 to 1% of all causes of bowel obstruction. A 59-year-old patient presented acuetly with small bowel obstruction. Laparotomy revealed a left paraduodenal hernia with most of the small bowel herniating through a space between the inferior mesenteric vein and duodenojejunal junction.