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Strategies to improve diagnosis and access to treatment of retinoblastoma in low-and middle-income countries: a systematic review
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  • Bruna Rabelo,
  • Kevin de Alvarenga,
  • Karla Emília Rorigues,
  • Adeylson Ribeiro,
  • Luiz Lopes
Bruna Rabelo
Hospital de Cancer de Barretos

Corresponding Author:[email protected]

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Kevin de Alvarenga
Universidade Federal de Minas Gerais
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Karla Emília Rorigues
Hospital de Cancer de Barretos
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Adeylson Ribeiro
Hospital de Cancer de Barretos
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Luiz Lopes
Hospital de Cancer de Barretos
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Retinoblastoma, the most common intraocular tumor in childhood, still faces challenges in diagnosis and treatment, particularly in low- and middle-income countries. Identifying strategies to improve the time to diagnosis and access to treatment is crucial to enhance survival rates and preserve ocular health. We conducted a systematic review to identify interventions that have demonstrated potential in addressing these challenges. We performed a comprehensive search across databases until March 2023. Out of the studies reviewed, twenty-one met the inclusion criteria and were categorized into five main areas: surveillance strategies, genetic counseling, education, public assistance and international partnership. Despite the obstacles faced, the initiatives identified in this review present acts towards improving the time to diagnosis and access to treatment for retinoblastoma. Based on the extracted data, we propose a comprehensive chain of initiatives. We firmly believe that implementing this chain of initiatives can lead to improved clinical outcomes for retinoblastoma patients.
Submitted to Pediatric Blood & Cancer
20 Feb 2024Review(s) Completed, Editorial Evaluation Pending
22 Feb 2024Editorial Decision: Revise Minor
01 Mar 20241st Revision Received
01 Mar 2024Assigned to Editor
01 Mar 2024Submission Checks Completed
18 Mar 2024Editorial Decision: Accept