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Commensal microbiome and gastrointestinal mucosal immunity: harmony and conflict with our closest neighbor
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  • Tingting Wang,
  • Kexin Tian,
  • Junzhe Lan,
  • Dehong Jing,
  • Mingming Lv
Tingting Wang
Nanjing University

Corresponding Author:[email protected]

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Kexin Tian
Nanjing University Medical School
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Junzhe Lan
Nanjing University
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Dehong Jing
Nanjing University
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Mingming Lv
Nanjing University
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Abstract

The intestinal mucosal immune system is a specialized immune system that interacts closely with commensal microorganisms. The intestinal mucosal tissues are characterized by the way they generate immune responses to pathogens. The symbiotic flora in turn regulates the host's mucosal immunity, maintaining a dynamic balance. The disruption of the equilibrium between the two can result in intestinal disorders. This paper summarises in depth the relationships between the two and serves as a resource for future research.