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The Use of Extracorporeal Membrane Oxygenation as a Bridge to Bone Marrow Transplantation in a Patient with High Risk Acute Myeloid Leukemia
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  • Marie Nader,
  • Pramod Bonde,
  • Stephanie Massaro,
  • John Giuliano,
  • Niketa Shah
Marie Nader
Yale-New Haven Children's Hospital

Corresponding Author:[email protected]

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Pramod Bonde
Yale School of Medicine
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Stephanie Massaro
Yale School of Medicine
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John Giuliano
Yale School of Medicine
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Niketa Shah
Yale School of Medicine
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Abstract

An 18-year-old girl with high risk acute myeloid leukemia developed Streptococcus mitis septic shock and multi-organ dysfunction syndrome, including biventricular failure. Due to the anticipated reversibility of her cardiogenic shock, her young age and her favorable survival chance following allogeneic hematopoietic stem cell transplant, she was placed on full circulatory support with veno-arterial extracorporeal membrane oxygenation as a bridge to her successful HSCT two months later. This highlights the importance of prognostication in patient selection for extracorporeal life support. A multi-disciplinary approach is essential to each case until better initiation criteria, risk stratification and treatment protocols are established.