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Unusual Case of Histiocyte-Rich Rhabdomyoblastic Tumor in a Pediatric Patient
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  • Lenka Krskova,
  • BArbora Šípalová,
  • Jan Balko,
  • Simona Zimová,
  • Dagmar Voříšková,
  • Petr Broz,
  • Roman Kodet,
  • avicha Vícha
Lenka Krskova
2nd Faculty of Medicine,Charles University Prague

Corresponding Author:[email protected]

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BArbora Šípalová
2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital
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Jan Balko
2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital
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Simona Zimová
2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital
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Dagmar Voříšková
2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital
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Petr Broz
2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital
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Roman Kodet
2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital
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avicha Vícha
2nd Medical Faculty, Charles University and University Hospital Motol
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Abstract

Histiocyte-rich skeletal rhabdomyoblastic tumor (HR-RMT) is a rare recently described skeletal muscle neoplasm of uncertain malignant potential. We report an unusual tumor in the right arm of a 5-year-old boy, which is the first case of a pediatric HR-RMT. Immunohistochemically, most cells in the tumor were positive for CD163 and CD68 staining. The neoplastic cells themselves showed a skeletal muscle phenotype with diffuse expression of desmin and focal expression of myoD1. Mitotic activity was low (1/10 HPF) and no necrosis was observed.