Evolution of Adverse drug reactions reporting systems: Paper-based to
Abstract Adverse Drug Reactions (ADR) add a significant clinical and
economic burden to the healthcare system of a country. Reporting ADRs is
the cornerstone of detecting uncommon ADRs once the drugs are on the
market. In many countries, ADR reporting is regulated by national
regulatory bodies and various methods are employed to report ADRs.
Direct reporting by healthcare professionals has been adopted by many
developed and developing countries. We present an overview of the
different approaches of ADR reporting systems worldwide and their
evolution over time.