Risk factors for catheter-related infection in children with cancer: a
systematic review and meta-analysis
Rationale: To understand the risk factors for catheter-related infection
during treatment of pediatric cancer is essential to implement measures
to prevent its occurrence. Methods: We performed a systematic review of
the literature with meta-analysis to identify and synthesize the main
risk factors for catheter-related infection in children with cancer.
Systematic searches were conducted in Medline, Embase, Lilacs, and BVS.
Results: Thirteen studies were included. Risk factors were divided into
host-related, assistance-related, and catheter types. Diagnosis of
hematological neoplasm, the intensity of treatment, blood transfusion in
the 4-7 days before the infection, type of long-term catheters,
inpatient treatment, and a longer period of hospitalization were the
most consistent risk factors. Conclusions: Education for preventive
measures, reduction of hospitalization, wisely choosing the most
adequate type of catheter, and the best moment for catheter insertion
may reduce the occurrence of catheter-related infection.