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Does vitamin D cause atopy?
  • Valeria Andrea Zúñiga,
  • Blanca Bazan-Perkins
Valeria Andrea Zúñiga
Instituto Tecnologico y de Estudios Superiores de Monterrey Escuela de Medicina y Ciencias de la Salud

Corresponding Author:[email protected]

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Blanca Bazan-Perkins
Instituto Nacional de Enfermedades Respiratorias
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Due to the Covid-19 pandemic, the intake of vitamin D (VD) has increased. Vitamin D has multiple regulatory effects in the human body, including immunological. Evidence accentuates the generation of a pro-tolerogenic T helper (Th) 2 cell state with VD, suppressing a Th1 inflammatory response. Th2 cell polarization is characteristic of atopy. However, VD promotes a balanced state through the action of regulatory T cells, controlling cytokines, both pro-inflammatory and anti-inflammatory, and by reducing B cell proliferation and differentiation, thus preventing the development of atopy.