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Assessment of hematological parameters in typhoid fever.
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  • Syed Raza,
  • Hina Jawaid,
  • Imtiaz Tahir,
  • Abid Rashid
Syed Raza

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Hina Jawaid
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Imtiaz Tahir
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Abid Rashid
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Introduction: Typhoid fever is an acute, generalized infection of the reticuloendothelial system, which is caused by Salmonella typhi and causes substantial and hepatic complications and biochemical changes. Currently, the diagnostic test is isolation of bacteria from blood, stool and occasionally urine, but serologic tests are still commonly used, and there is still a necessity for the rapid and reliable diagnostic test for typhoid fever. The objective of this study was to determine the hematological changes in adult typhoid patients as compared to healthy control. Methodology: A total of 50 patients and 50 healthy individuals were enrolled in this research, and variations in hematological factors were studied. Results: Hematological parameters were found deranged in typhoid fever including hemoglobin (low, 10.97±0.88), hematocrit (low, 37.72±1.40), ESR (high 45.08±13.42), platelet count (high 588840±97185), WBCs count (high 38267±22279), neutrophil percentage (high, 73.56±9.96), lymphocyte percentage (low, 21.24±10.08), and NLCR (high, 5.14±4.00) as compared to healthy control group. Conclusion: This differentiating pattern is easy to obtain by minimal invasive procedure and can be used for typhoid infection diagnosis.