Re: Effectiveness of hypertonic saline nebulization in airway clearance
in children with non-cystic fibrosis bronchiectasis: a randomized
AbstractThis first RCT of hypertonic saline use in pediatric non-CF
bronchiectasis patients uses a cross over design and demonstrates an
improvement in predicted FEV1 and FVC. Limitations include lack of
blinding and risk of information bias, as well as reduced precision due
to absence of within subject comparisons.