Serum ischemia-modified albumin as an oxidative stress biomarker in lung
Aim of Study: The goal of this study was to evaluate ischemia-modified
albumin (IMA) as a novel marker of oxidative stress in tuberculosis
patients and to investigate changes occurring in patients. Methods: Our
study included 50 patients with active lung tuberculosis and 48 healthy
controls. Serum ischemia-modified albumin was measured with automated
spectrometric method and results were compared statistically. Results:
We found that IMA levels were significantly higher in pulmonary
tuberculosis patients than in the control group. Albumin levels were
significantly lower in the patient group than in the control group.
Conclusion: The results of our study showed that we can use this
parameter as a new oxidative stress marker in the pathogenesis of
pulmonary tuberculosis. Evaluation of IMA and albumin parameters in
patients with pulmonary tuberculosis may contribute significantly to the
evaluation of these patients.