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Correlations between risk factors and clinical features in patients with cerebellar infarction: A new perspective based on clinical data
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  • Peijun Wang,
  • Lai Wei ,
  • Kangwei Zhang,
  • Jinqian Meng,
  • Jiong Ni
Peijun Wang

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Kangwei Zhang
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Jinqian Meng
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Abstract

Background: Cerebellar infarction in different populations have different characteristics. This study analyzed the correlations between the risk factors, etiology, distribution of blood vessels involved, infarct lesion size and scope, and blood glucose, blood lipids and D-dimer levels. Methods: A total of 83 patients with acute cerebellar infarction were included in this analysis. The NIHSS score and TOAST classification were evaluated independently by double blind. Head CT and MRI examinations were performed and CTA and MRA were carried out subsequently. The levels of blood lipids, blood glucose and D-dimer were analyzed by automatic biochemical analyzer. Results: Carotid atherosclerosis (97.6%), hyperlipidemia (66.3%) and hypertension (77.1%) were the main risk factors for cerebellar infarction in these patients. Ataxia (67.5%) and brainstem syndrome (60.2%) were main clinical manifestations. SAO (43.3%) and LAA (50.6%) accounted for the majority of TOAST classifications. The number of patients with cerebellar infarction caused by SCA stenosis was significantly higher than that caused by other blood supply arteries (P<0.05). CTA and MRA are equivalent in displaying narrow cerebellar artery (P>0.05), but compared with CT, MRI has absolute advantages in displaying the lesions of cerebellar infarction (P<0.05). The serum concentrations of D-dimer, HDL, LDL, and triglycerides are correlated with the patient’s NIHSS scores, TOAST classification and lesion size (P<0.05). Conclusions: The occurrence of cerebellar infarction is directly related to hypertension, hyperlipidemia and carotid atherosclerosis. CTA and MRA are equivalent in showing narrow blood vessels but MRI showed an absolute advantage in showing the lesion of cerebellar infarction compared with CT. The serum concentrations of D-dimer, HDL, LDL, and triglycerides are helpful to the diagnosis and evaluation of cerebellar infarction.