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Lung Cancer Screening Results Among Population of Different Genders, Ages, Smokers and Non-smokers: A Study Based on Real World Data
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  • Ting Bao,
  • Zhenzhen Li,
  • Guiyi Ji,
  • Huairong Tang,
  • Youjuan Wang,
  • Ping Yang,
  • Hanwei Yang,
  • Weimin Li,
  • Yan Huang
Ting Bao
Sichuan University West China Hospital
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Zhenzhen Li
Sichuan University West China Hospital
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Guiyi Ji
Sichuan University West China Hospital
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Huairong Tang
Sichuan University West China Hospital
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Youjuan Wang
Sichuan University West China Hospital
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Ping Yang
Mayo Clinic College of Medicine and Science
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Hanwei Yang
Sichuan University West China Hospital
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Weimin Li
Sichuan University West China Hospital
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Yan Huang
Sichuan University West China Hospital

Corresponding Author:[email protected]

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Abstract

Background Analysis of the real-world data of low-dose spiral CT screening of healthy physical examination population in Southwest China from 2006 to 2017, discussed the standard of low-dose spiral CT screening for high-risk population of lung cancer in China. Methods Incorporate all team subjects who have undergone LDCT screenings at the Health Management Center of West China Hospital of Sichuan University between 2006 and 2017, and analyze the cumulative incidence and age-standardized (Segi population) incidence of lung cancer in the whole population; finally, analysis the age-specific, smoking and non-smokers’ lung cancer incidence. Results A total of 15,996 people who met the enrollment conditions and participated in the LDCT lung cancer screening were included. The average screening interval was 1.12±0.26 years, and the average follow-up time was 5.43±0.82 years; The cumulative number of lung cancer cases with negative baseline screening was 56 cases, and the cumulative incidence rate of lung cancer was 122.1/100,000 (the world standard rate is 60.6/100,000), of which males were 100.0/100,000 (the world standard rate is 45.3/100,000) and women were 156.6 /100,000 (the world standard rate is 94.7/100,000); the cumulative incidence of lung cancer in the smoking group is higher than that in the non-smoking group for both males and females, but the cumulative incidence of lung cancer in the non-smokers of the female population (146.3/100,000) is higher than that of the male population (86.5/10 Million). Conclusion In the real world study of lung cancer screening in Chinese population, we should consider setting different standards for high-risk groups of lung cancer by gender or smoking and non-smokers.