Laryngeal chondrosarcoma associated to cervical lymph node metastasis of
papillary thyroid carcinoma. A systematic review.
Objective: Laryngeal chondrosarcomas (LCS) are rare tumors with good
prognosis. The coexistence of LCS and cervical metastasis of papillary
thyroid carcinoma (PTC) is scarce. The main objective of this research
was to review clinical aspects and management of LCS . A secondary
objective was to find the coexistence of LCS with cervical Lymph node
metastasis of papillary thyroid carcinoma (LNMPTC) in all the cases
included in the search. Design: A Systematic Review was performed using
PubMed, Web of Science, Scopus and Embase databases. We followed PRISMA
guidelines and the PECOS method to characterize different aspects of
LCS. Reports of laryngeal chondrosarcoma were included and information
about symptoms, imaging technique, treatment modality, histopathological
diagnosis, location, tumor size, recurrence, and follow-up data was
extracted. Results: Three hundred and eighty one cases of LCS were
included. The average age was 61.1 years. The most common symptoms were
dyspnea and hoarseness. Cricoid cartilage was the most usual location.
Survival was affected by histologic differentiation, tumoral location
and surgical technique. We identified the coexistence of LCS and PTC in
2 cases. In none of them the authors reported LNMPTC. Conclusion: The
coexistence of LCS and PTC is rare. LCS is a tumor with good prognosis.
Different approaches are described in literature.