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Use of thromboelastometry-guided surgery in a pediatric patient with adrenal neuroblastoma complicated with disseminated intravascular coagulation.
  • +6
  • MR Pérez-Torres Lobato,
  • Maria Molina,
  • Mercedes Livia Llempén López ,
  • Israel Fernández Pineda,
  • Rosa Cabello,
  • Eloy Rivas Infante ,
  • Cristina Hernández Herrera,
  • Catalina Márquez-Vega,
  • Javier Rodrigez Martorell
MR Pérez-Torres Lobato
Virgen del Rocio University Hospital

Corresponding Author:[email protected]

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Maria Molina
Virgen del Rocio University Hospital
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Mercedes Livia Llempén López
Virgen del Rocio University Hospital
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Israel Fernández Pineda
Virgen del Rocio University Hospital
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Rosa Cabello
Virgen del Rocio University Hospital
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Eloy Rivas Infante
Virgen del Rocio University Hospital
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Cristina Hernández Herrera
Virgen del Rocio University Hospital
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Catalina Márquez-Vega
Virgen del Rocio University Hospital
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Javier Rodrigez Martorell
Virgen del Rocio University Hospital
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Abstract

Disseminated intravascular coagulation (DIC) is a rare oncological emergency. We report a pediatric neuroblastoma complicated with DIC which required thromboelastometry-guided surgery. A 6-year-old female diagnosed with intermediate risk adrenal neuroblastoma developed tumor-related DIC after chemotherapy first cycle. She remained stable without clinical bleeding and emergent tumor resection guided by intraoperative-thromboelastometry was decided. DIC resolved early after surgery and complete remission was achieved. Treatment of the underlying condition is critical to manage DIC. Thromboelastometry can guide goal-directed therapy, including surgery in pediatric patients. However, larger studies are needed to examine its applicability in different clinical settings, such as cancer related DIC.