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The association between enteral feeding with survival of critical patients with COVID-19 patients
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  • Maryam Gholamalizadeh,
  • Zahra Salimi,
  • Khadijeh Abbasi Mobarakeh,
  • Zahra Mahmoudi,
  • Shirin Tajadod,
  • Mehdi Moosavi,
  • Farkhondeh Alami,
  • Bojlul Bahar,
  • Saeid Doaei,
  • Sara khoshdooz,
  • Masoume Rahvar,
  • Somayeh Gholami ,
  • Masoume Pourtaleb
Maryam Gholamalizadeh
Shahid Beheshti University of Medical Sciences
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Zahra Salimi
Ahvaz Jundishapur University of Medical Sciences
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Khadijeh Abbasi Mobarakeh
Isfahan University of Medical Sciences
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Zahra Mahmoudi
Hamadan University of Medical Sciences
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Shirin Tajadod
Iran University of Medical Sciences
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Mehdi Moosavi
Hamadan University of Medical Sciences
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Farkhondeh Alami
Urmia University of Medical Sciences
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Bojlul Bahar
University of Central Lancashire
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Saeid Doaei
Shahid Beheshti University of Medical Sciences

Corresponding Author:[email protected]

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Sara khoshdooz
Guilan University of Medical Sciences
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Masoume Rahvar
Guilan University of Medical Sciences
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Somayeh Gholami
Guilan University of Medical Sciences
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Masoume Pourtaleb
Guilan University of Medical Sciences
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Abstract

Background: Coronavirus disease 2019 (COVID-19) results in several complications and mortality in ICU patients. The effect of enteral nutrition on the survival of COVID-19 patients in the ICU has been investigated in limited instances. The aim of this study is to investigate the association of enteral feeding with biochemical and pathological indices associated with mortality in COVID-19 patients. Methods: This case-control study was conducted on 240 patients with COVID-19 hospitalized in the ICU including 120 eventually dead patients as the cases and 120 discharged patients as the controls. All of the patients received enteral nutrition. Data on general information, anthropometric measurements, and the results of lab tests were collected. Results: The recovered patients received significantly more high protein (60.8% vs. 39.6%, P=0.004) and high volume (61.6% vs. vs. 42.3%, P=0.005) formula compared to the dead patients. Mortality was inversely associated with high volume (OR:0.45 CI95%, P=0.008) and high protein formula (OR:0.42 CI95%, P=0.003). The results remained significant after adjusting for age and sex. Further adjustment for underlying diseases and smoking, BMI, and APACHII did not change the results. Conclusion: The findings of the study showed that there was a significant inverse association between mortality and high volume and high protein formula in COVID-19 patients that warrants further investigation.
12 Aug 2023Submitted to Immunity, Inflammation and Disease
17 Aug 2023Assigned to Editor
17 Aug 2023Submission Checks Completed
21 Aug 2023Review(s) Completed, Editorial Evaluation Pending
23 Aug 2023Reviewer(s) Assigned