The DC-T cell axis is a bridge connecting innate immunity and adaptive
immunity. The initial immune response against tumors is mainly induced
by mature antigen-presenting dendritic cells (DC). Enhancing the
crosstalk between DC and T cells could improve the immune response to
non-small cell lung cancer. This article reviews the interaction between
DC-T cells in the treatment of non-small cell lung cancer and how this
interaction impacts the treatment outcome.