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Evaluation of the effect of glutathione on nanozymatic activity of enzyme-like carbon dots     
  • Saeed Reza Hormozi Jangi
Saeed Reza Hormozi Jangi

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Abstract

The effect of the glutathione molecules as a possible inhibitor was investigated on the nanozymatic activity of the enzyme-like carbon dots.  The peroxidase-like activity of carbon dots was proved via catalysis of peroxidase-mediated oxidation of TMB as a standard peroxidase substrate. The experimental investigations exhibited that the peroxidase-like activity of the carbon dots was significantly inhibited by glutathione molecules. Hence, the inhibitory effect of glutathione molecules on their nanozymatic activity was evaluated, revealing that the relative activity of nanozymes was inhibited by increasing the glutathione concentration in the reaction media, revealing a strong inhibitory effect of glutathione molecules on the nanozymatic activity of the enzyme-like carbon dots.