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Triclosan Allergy Mimicking Recurrent CIED Infections
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  • George H. Crossley,
  • Jamie Kowal,
  • Karen Bloch,
  • Jane Phillips,
  • Basil Kawash
George H. Crossley
Vanderbilt University Division of Cardiovascular Medicine

Corresponding Author:[email protected]

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Jamie Kowal
Vanderbilt University Division of Infectious Diseases
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Karen Bloch
Vanderbilt University School of Medicine
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Jane Phillips
Vanderbilt University School of Medicine
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Basil Kawash
Vanderbilt University School of Medicine
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Abstract

An 80-year-old man had a secondary prevention defibrillator in place for treatment of sustained ventricular tachycardia. After a generator replacement several years later, he developed a series of apparent pulse generator infections requiring extraction. Each purulent appearing pocket eruption was culture negative. Eventually, he was diagnosed with a delayed hypersensitivity reaction to triclosan, an antibacterial that is commonly impregnated in surgical sutures. The evaluation for this is difficult and can be misleading. This entity should be considered in the differential diagnosis of patients with culture negative CIED infections.
19 Sep 2023Submitted to Journal of Cardiovascular Electrophysiology
30 Oct 2023Assigned to Editor
30 Oct 2023Submission Checks Completed
30 Oct 2023Review(s) Completed, Editorial Evaluation Pending
11 Nov 2023Reviewer(s) Assigned
20 Nov 2023Editorial Decision: Revise Minor