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Immersive Virtual Reality for symptom management in breast cancer patients:a systematic review and meta-analysis of Randomized Control Trial
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  • qunhong Zhang,
  • Zhongzheng Li,
  • Jichuan Shen,
  • Qiuyue Song
qunhong Zhang
Jishou University School of Medicine
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Zhongzheng Li
Jishou University School of Medicine
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Jichuan Shen
Jishou University School of Medicine
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Qiuyue Song
The Fourth Affiliated Hospital of Jishou University(Hunan University of Medicine Geaneral Hospital)

Corresponding Author:[email protected]

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Design: A systematic review according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses(PRISMA) 2020 Statement. It is registered in the Prospective Registry of International Systematic Reviews (PROSPERO) database. (Registration number: CRD42023447007).[PubMed, Embase, The Cochrane Library, Web of Science, CNKI, Wanfang Data Knowledge Service Platform, and Chinese Scientific and Technical Journal Database (VIP) were searched from the library’s construction to August 1, 2023. Methods: After literature screening, data extraction, and evaluation of literature quality were independently performed by 2 researchers trained in evidence-based care according to the inclusion and exclusion criteria, and meta-analysis was performed using RevMan 5.4. Results: A total of 6 randomized controlled trials containing 531 patients were included. Meta-analysis showed that IVR-based interventions helped to improve anxiety symptoms [SMD=-2.06,95% CI= (-2.73,-1.40), P<0.0001], depressive symptoms [SMD=-2.31,95% CI=(-4.39,0.23), P=0.03] and fatigue symptoms [SMD=-1.94,95%CI=(-3.18,-0.71), P=0.002]; the qualitative analysis results showed that IVR technology could improve the pain and the quality of life of breast cancer patients, and the difference was statistically significant (P<0.05). Conclusions: IVR technology applied to breast cancer patients can improve their anxiety, depression, pain, fatigue, and other symptoms, and improve their quality of life, and it is interesting and worth promoting. Due to the limited number of included studies and sample size, more large-sample trials are to be conducted to explore the applicability and feasibility of IVR technology in symptom management of breast cancer patients and to validate the above results.
17 Oct 2023Submitted to Cancer Reports
17 Oct 2023Review(s) Completed, Editorial Evaluation Pending
17 Oct 2023Assigned to Editor
17 Oct 2023Submission Checks Completed
22 Oct 2023Reviewer(s) Assigned