loading page

Fast Fluorescence Sensing of Aflatoxin B1 Employing a Europium Metal--Organic Framework Avoiding Self-Fluorescence Interference of Target
  • +8
  • Mingzhu Liu,
  • Zunquan Zhao,
  • Jingran Sun,
  • Yonghui Wang,
  • Xiaoli Li,
  • Yanjun Fang,
  • Jian Hou,
  • Yixue Fu,
  • Lingchao Cai,
  • Jin Wu,
  • Jialei Bai
Mingzhu Liu
Tianjin Institute of Environmental and Operational Medicine
Author Profile
Zunquan Zhao
Tianjin Institute of Environmental and Operational Medicine
Author Profile
Jingran Sun
Tianjin Institute of Environmental and Operational Medicine
Author Profile
Yonghui Wang
Tianjin Institute of Environmental and Operational Medicine
Author Profile
Xiaoli Li
Tianjin Institute of Environmental and Operational Medicine
Author Profile
Yanjun Fang
Tianjin Institute of Environmental and Operational Medicine
Author Profile
Jian Hou
Tianjin Institute of Environmental and Operational Medicine
Author Profile
Yixue Fu
Tianjin Institute of Environmental and Operational Medicine
Author Profile
Lingchao Cai
Nanjing Forestry University
Author Profile
Jin Wu
Tianjin Institute of Environmental and Operational Medicine
Author Profile
Jialei Bai
Tianjin Institute of Environmental and Operational Medicine

Corresponding Author:[email protected]

Author Profile

Abstract

The rapid monitoring of food safety plays a key role in the food industry. Here, we have prepared a lanthanide metallo-organic framework Eu-TCPP, which can selectively detect aflatoxin B1, showing an ultrafast response of 5 min, a detection limit (LOD) of 44.17 ng/mL, and potential to develop point-of-care testing (POCT) sensing materials. Moreover, the emission wavelength of Eu-TCPP is at 617nm, which can effectively avoid aflatoxin autofluorescence interference, which is rarely reported in other mycotoxin fluorescence detection sensors. Combined experimental analysis and density functional theory (DFT) calculations show that the high selectivity, high sensitivity and rapid response ability of Eu-TCPP to detect aflatoxin B1 may be due to the LUMO level of the ligand higher than the LUMO level of aflatoxin, which transfers electrons to the object to be detected, resulting in weakened fluorescence. This study not only provides a potential probe for aflatoxin detection, but also providing a horizon that can guide the development of sensing materials for point-of-care testing (POCT) application.