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Medium- and long-chain triacylglycerol in human breast milk and association with maternal dietary patterns
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  • Jingru Gong,
  • Lei Wang,
  • Xingguo Wang,
  • Wei Wei
Jingru Gong
Jiangnan University
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Lei Wang
Jiangnan University
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Xingguo Wang
Author Profile
Wei Wei
Jiangnan University

Corresponding Author:[email protected]

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This study aims to investigate the influences of maternal dietary patterns on the triacylglycerol (TAG) composition, particular medium- and long-chain triacylglycerol (MLCT) in human breast milk. A total of 180 Chinese human breast milk samples were collected and divided into three dietary patterns groups accounting to semi-quantitative food intake frequency questionnaire and a 24-hour dietary recall. Using high performance liquid chromatography combined with quadrupole time-of-flight mass spectrometry, 108 TAGs were identified and quantified. In breast milk samples, MLCTs accounted for 25.76 % (median of 24.63%; 95% CI: 24.60, 26.92) of the total TAGs. In human breast milk, the main type of MLCT is TAGs esterified with one medium-chain fatty acid and two long-chain fatty acids (MLL type) which accounted for ~81% of total MLCTs. Among the molecular species of MLCT, O-P-La, O-L-La, and O-L-M are the three most abundant configurations in MLCT (2.28%, 2.17%, and 2.01% of total TAGs, respectively). MLCT in breast milk was positively correlated with the energy supply ratio of carbohydrates (P = 0.205), which was significantly higher than that of the other two groups (P = −0.150 and −0.232).
31 Aug 2023Submitted to Journal of the American Oil Chemists' Society
31 Aug 2023Submission Checks Completed
31 Aug 2023Assigned to Editor
03 Sep 2023Review(s) Completed, Editorial Evaluation Pending
08 Sep 2023Reviewer(s) Assigned
08 Nov 20231st Revision Received
08 Nov 2023Submission Checks Completed
08 Nov 2023Assigned to Editor
08 Nov 2023Review(s) Completed, Editorial Evaluation Pending
10 Nov 2023Reviewer(s) Assigned