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Divergent Synthesis of New Naphtho-Fused 2-Aminoindolines and Naphthoxindoles Based on Straightforward Construction of Phenanthrene
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  • Bin Qiu,
  • Ya-Fei Shi,
  • Xiao-De An,
  • Shu-Kui Guo,
  • Yao-Bin Shen,
  • Jian Xiao
Bin Qiu
Qingdao Agricultural University

Corresponding Author:[email protected]

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Ya-Fei Shi
Qingdao Agricultural University
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Xiao-De An
Qingdao Agricultural University
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Shu-Kui Guo
Qingdao Agricultural University
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Yao-Bin Shen
Zaozhuang University
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Jian Xiao
Qingdao Agricultural University
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Abstract

A secondary amine-controlled 4-step cascade aldimine condensation/intramolecular Mannich-type cyclization/aromatization/amination or oxidation process, using biaryls aldehydes and secondary amines as substrates, has been developed to divergently assemble naphtho-fused 2-aminoindolines and naphthoxindoles in a one-pot reaction.