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Association of catalase promoter haplotype and catalase level in the X-ray employments
  • Zahraa Sami Razzaq Najjar,
  • Zainab Mahdi Jasim Al-Saygh,
  • Mona N. Al-Terehi
Zahraa Sami Razzaq Najjar
University of Kufa Faculty of Education

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Zainab Mahdi Jasim Al-Saygh
University of Kufa Faculty of Education
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Mona N. Al-Terehi
University of Babylon
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Abstract

the current study aims to detect Association of catalase promoter haplotype and catalase level and its relation with ROS in the X-ray employments , the results show that the mean of employments age was (36.90±2.330) and (39.23±0.06760) for control group , The level of CAT showed significant reduction in X-ray employments group (0.701±0.067) (p= 0.000), and non-significant differences observed in both groups that have approximately same results in ROS levels (p= 0.810), The correlation between CAT level and different work times in the X-ray employments group show inverse correlation with work time per day, and positive association with other times of working in non-significant differences, belong to ROS there was significant inverse correlation with work time per day and non-significant inverse relation with direct exposure per day and per week, the (CAT -89A>T) haplotypes detected using PCR-SSCP technique, the results show two types of haplotypes (single and double haplotypes) a strong association of double haplotypes with employments group (p= 0.000) was observed. The results concluded that there was significant reduction of CAT level and (CAT -89A>T) haplotypes with group exposed to X-ray radiation.