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Title Successful Prenatal Treatment with Continuous Chronic Maternal Hyperoxygenation Therapy in Hypoplastic Left Heart in Two Pregnancies: Case report
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  • Ali Gedikbasi,
  • Gokhan Bolluk,
  • Aylin Oztarhan,
  • Cagdas Vural,
  • Kazim Oztarhan
Ali Gedikbasi
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Corresponding Author:[email protected]

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Gokhan Bolluk
Basaksehir Cam ve Sakura Sehir Hastanesi
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Aylin Oztarhan
Istanbul Sisli Hamidiye Etfal Egitim ve Arastirma Hastanesi Kardiyoloji Klinigi
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Cagdas Vural
Eskisehir Sehir Hastanesi
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Kazim Oztarhan
─░stanbul Medical School Division of Pediatric Cardiology
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ABSTRACT Maternal hyperoxygenation (MH) has been studied as a diagnostic tool to evaluate pulmonary vasculature and as a treatment option to improve the growth of fetal left heart in fetuses with left-sided cardiac defects. Chronic maternal hyperoxygenation (CMH) therapy leads to an improvement in fetal pulmonary blood flow resulting in an enhanced venous return to the left heart with increased gestational age. With this manipulation it is anticipated to augment blood flow directed remodeling of the left heart structures and to improve left heart growth spanning from the mitral valve to the aortic isthmus. However, there are concerns about CMH therapy with regard to fetal complications with growth restriction and fetal brain development. Now, with two successful cases we try to discuss this fetal treatment option and related concerns.
07 Jul 2023Submitted to Echocardiography
07 Jul 2023Submission Checks Completed
07 Jul 2023Assigned to Editor
23 Jul 2023Reviewer(s) Assigned
27 Aug 2023Review(s) Completed, Editorial Evaluation Pending
30 Aug 2023Editorial Decision: Revise Minor
04 Sep 20231st Revision Received
05 Sep 2023Submission Checks Completed
05 Sep 2023Assigned to Editor
05 Sep 2023Reviewer(s) Assigned
12 Sep 2023Review(s) Completed, Editorial Evaluation Pending
25 Sep 2023Editorial Decision: Accept