loading page

Resolution pharmacology and the treatment of infectious diseases.
  • +1
  • Vivian Costa,
  • Filipe Resende,
  • Eliza Melo,
  • Mauro Teixeira
Vivian Costa
Author Profile
Filipe Resende
Federal University of Minas Gerais
Author Profile
Eliza Melo
Universidade Federal de Minas Gerais
Author Profile
Mauro Teixeira
Universidade Federal de Minas Gerais Instituto de Ciências Biológicas

Corresponding Author:[email protected]

Author Profile


Inflammation is a physiological response composed by well-defined and overlapping events that can eliminate pathogens and reestablish homeostasis of tissues. Physiological systems have an elastic capacity to deal with numerous perturbations. Infection may lead to inflammation, tissue damage and disease as consequence of breakdown of tissue resilience. The resolutive phase is a sine qua non condition to achieve homeostasis after acute inflammation. Exuberant or chronic inflammation occurs in diverse infectious diseases. Pro-resolving molecules may be useful for the treatment of certain infections, as these molecules modulate the immune response and avoid the exacerbated/misplaced inflammation unleashed by microbes. Some pro-resolving molecules may also favour pathogen clearance, in addition to decreasing tissue damage. In this review, we discuss the endogenous role and the therapeutic potential of the most relevant pro-resolving molecules in the context of bacterial and viral infections.
28 Jun 2023Submitted to British Journal of Pharmacology
29 Jun 2023Submission Checks Completed
29 Jun 2023Assigned to Editor
04 Jul 2023Reviewer(s) Assigned
25 Jul 2023Review(s) Completed, Editorial Evaluation Pending
27 Jul 2023Editorial Decision: Revise Minor
13 Sep 20231st Revision Received
14 Sep 2023Submission Checks Completed
14 Sep 2023Assigned to Editor
17 Sep 2023Reviewer(s) Assigned
09 Oct 2023Review(s) Completed, Editorial Evaluation Pending
26 Oct 2023Editorial Decision: Revise Minor