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Red Cell Transfusions in Children with Thalassemia; Outcomes of a10mL/kg/hr Infusion Rate
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  • Stephanie FritchLilla,
  • Amy Goldstein,
  • Nicole Hart,
  • Casey Hooke
Stephanie FritchLilla
Children's Minnesota

Corresponding Author:[email protected]

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Amy Goldstein
Children's Minnesota
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Nicole Hart
Children's Minnesota
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Casey Hooke
Children's Minnesota
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Children with transfusion dependent thalassemia have an impaired ability to synthesize alpha or beta globin which results in anemia. Packed red blood cell (PRBC) transfusions are required to increase hemoglobin which supports appropriate growth and development. PRBC transfusions must be completed with 4 hours however infusion rates vary across institutions. Our institution infuses PRBC’s up to 10mL/kg/hr. A descriptive study of 21 children who received a total of 276 transfusions during 2021 demonstrated that this rate is safe and well tolerated. Shorter transfusion times support patients’ and families’ time, resources, and quality of life and aptly utilize institutional resources.
12 Jun 2023Submission Checks Completed
12 Jun 2023Assigned to Editor
12 Jun 2023Submitted to Pediatric Blood & Cancer
14 Jun 2023Review(s) Completed, Editorial Evaluation Pending
17 Jun 2023Reviewer(s) Assigned
04 Jul 2023Editorial Decision: Revise Minor
12 Jul 2023Submission Checks Completed
12 Jul 2023Assigned to Editor
12 Jul 20231st Revision Received
18 Jul 2023Review(s) Completed, Editorial Evaluation Pending
19 Jul 2023Editorial Decision: Accept