Comparative Antibacterial Efficacy of Honey and Ciprofloxacin Against
Selected Bacterial Pathogens.
Since ancient times, honey has been utilised as an alternative treatment
for some clinical diseases. This study investigates the antibacterial
potential of honey extracts obtained from Obanliku Hills in Cross River
State, Nigeria, against Staphylococcus aureus, Pseudomonas aeruginosa,
and Escherichia coli. Honey was extracted using successive solvent
extraction; Methanol, Ethyl acetate and n-Hexane were used as extraction
solvents. The bacteriostatic potential of all three extracts was
determined using well diffusion assay. Methanol and n-hexane extracts
showed no bacteriostatic impact, while the ethyl acetate extract
exhibited concentration-dependent bacteriostatic and bactericidal
effects. A significant (p<0.05) higher inhibition was observed
at 40 mg/ml of the honey extract compared to 10 mg/ml against all three
test organisms. In conclusion, honey extract had a greater bactericidal
effect against Staphylococcus aureus compared to E. coli and P.