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Comparative Antibacterial Efficacy of Honey and Ciprofloxacin Against Selected Bacterial Pathogens.
  • Ada Ada,
  • Ngozi Amaeze,
  • Sa’adatu Isa
Ada Ada
Terraskills Learning Systems Limited

Corresponding Author:[email protected]

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Ngozi Amaeze
University of Abuja
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Sa’adatu Isa
Agricultural Research Council of Nigeria (ARCN)
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Abstract

Since ancient times, honey has been utilised as an alternative treatment for some clinical diseases. This study investigates the antibacterial potential of honey extracts obtained from Obanliku Hills in Cross River State, Nigeria, against Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli. Honey was extracted using successive solvent extraction; Methanol, Ethyl acetate and n-Hexane were used as extraction solvents. The bacteriostatic potential of all three extracts was determined using well diffusion assay. Methanol and n-hexane extracts showed no bacteriostatic impact, while the ethyl acetate extract exhibited concentration-dependent bacteriostatic and bactericidal effects. A significant (p<0.05) higher inhibition was observed at 40 mg/ml of the honey extract compared to 10 mg/ml against all three test organisms. In conclusion, honey extract had a greater bactericidal effect against Staphylococcus aureus compared to E. coli and P. aeruginosa.