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Basic Clinical Management of Preschool Wheeze
  • Andrew Bush
Andrew Bush
Imperial College Business School

Corresponding Author:[email protected]

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Pre-school wheeze is very common and often difficult to treat. Most children do not require any investigations, only a detailed history and physical examination to ensure an alternative diagnosis is not being missed; the differential diagnosis, and hence investigation protocols for the child in whom a major illness is suspected, shows geographical variation. The pattern of symptoms may be divided into episodic viral and multiple trigger to guide treatment, but the pattern of symptoms must be re-assessed regularly. However, symptom patterns are a poor guide to underlying pathology. Attention to the proper use of spacers, and adverse environmental exposures such as tobacco smoke exposure, is essential. There are no disease-modifying therapies, so therapy is symptomatic. This paper reviews recent advances in treatment, including new data on the place of leukotriene receptor antagonists, prednisolone for acute attacks of wheeze and antibiotics, based on new attempts to understand the underlying pathology in a way that is clinically practical.
09 Jun 2023Submitted to Pediatric Allergy and Immunology
09 Jun 2023Assigned to Editor
09 Jun 2023Submission Checks Completed
09 Jun 2023Review(s) Completed, Editorial Evaluation Pending
13 Jun 2023Reviewer(s) Assigned
20 Jun 2023Editorial Decision: Accept