Oral Liposomal Iron: A promising new strategy for anemia management in
AbstractAnemia is a public health problem affecting about a third of the world's
population, the major cause of it being iron deficiency. The many oral
iron preparations available at present, are inadequate due to
intolerance, or contraindications. IV iron preparations are painful,
require patient monitoring and carry the risk of anaphylaxis. Iron salts
like Iron pyrophosphate are covered with liposome, a spherical structure
of a phospholipidic nature that is similar to those human cell
membranes. The bioavailability of liposomal pyrophosphate iron is 3.5
times greater than the free pyrophosphate iron, 2.7 times higher than
iron sulfate, and 4.1 times higher compared with iron gluconate.
Clinical studies showed that oral liposomal iron is a safe and
efficacious alternative to correct anaemia, as also it is a viable
treatment option for iron deficiency anaemia in pregnant women.